| Type | Description |
|---|---|
| Definition | topoisomerase 3alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 11:12:00 | A. thaliana TOP3alpha conserved zinc-finger domain (ZFD) T1 is specifically required for targeting the topoisomerase activity to Holliday junction like recombination intermediates to enable their processing. In the case of an inactivated enzyme, this leads to cell death due to the masking of these intermediates, hindering their resolution by MUS81. | 30222730 |
| 2015-07-25 11:10:00 | Data indicate that both topoisomerase3alpha (TOP3alpha) and RECQ4A/B helicases act independently of the anti-meiotic crossovers (COs) Fanconi anemia of complementation group M (FANCM) helicase. | 25825745 |
| 2010-01-21 00:00:00 | AtTOP3alpha and AtRMI1 are involved in the suppression of crossover recombination in somatic cells and DNA repair. | 19096507 |
| Type | IDs |
|---|---|
| Synonymous | AtTOP3alpha, MGI19.16, topoisomerase 3alpha |
| Gene |
UniProtKB-ID:
TOP3A_ARATH,
A0A654GDT9_ARATH
UniprotKB:
Q9LVP1,
A0A654GDT9
UniParc:
UPI00000AA5FC
EMBL:
EU295446,
CACRSJ010000110,
AB019227,
CP002688
EnsemblGenome:
AT5G63920
KO:
ath:AT5G63920
|
| Nucleutide sequences |
EMBL-CDS:
BAA96895.1,
ACA50279.1,
AED97816.1,
VYS71330.1
Gene_ORFName:
MGI19.16,
AN1_LOCUS26707
EnsemblGenome_TRS:
AT5G63920.1
|
| Protein sequencees |
EnsemblGenome_PRO:
AT5G63920.1
RefSeq:
NP_201197.1
|
| Others |
UniRef100:
UniRef100_Q9LVP1
UniRef90:
UniRef90_Q9LVP1
UniRef50:
UniRef50_Q9LVP1
UniGene:
At.28974
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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