| Type | Description |
|---|---|
| Definition | gamma-aminobutyric acid type B receptor subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 11:52:00 | Study provided evidence that GABAB2 subunit is involved in anxiety-like behaviours induced by chronic cerebral hypoperfusion. Activation of GABAB2 subunits could improve BDNF/TrkB/NCAM signalling and reverse Kir3 channel surface expressions in hippocampal CA1, which may alleviate the anxiety-like behaviours in rats with chronic cerebral hypoperfusion. | 27515806 |
| 2014-06-28 13:52:00 | this study shows that the trafficking and surface expression of GABABR2 and GABABR1 is differentially regulated by synaptic or pathophysiological activation of NMDA receptors. | 24425870 |
| 2014-06-28 11:54:00 | Gabbr2 exists in rat brain at birth and decreases between birth and PD15. | 24020808 |
| 2013-11-30 11:20:00 | siRNA knock-down of NgR1 resulted in a selective increase of GABAB R1 and GABAB R2 protein and an increase in GIRK1. | 23829864 |
| 2013-11-30 10:51:00 | GABABR activation reduces cyclic AMP-dependent phosphorylation of LKB1, a kinase involved in neuronal polarization, and rescues LKB1 overexpression-induced defects in cortical development. | 23653212 |
| Type | IDs |
|---|---|
| Synonymous | Gpr51 |
| Gene |
UniProtKB-ID:
GABR2_RAT
UniprotKB:
O88871
UniParc:
UPI000012B268
EMBL:
AF074482,
AF109405,
AJ011318,
AF058795
KO:
rno:83633
|
| Nucleutide sequences |
EMBL-CDS:
CAA09592.1,
AAD03335.1,
AAD03338.1,
AAC63994.1
|
| Protein sequencees |
RefSeq:
NP_113990.2
|
| Others |
UniRef100:
UniRef100_O88871
UniRef90:
UniRef90_O75899
UniRef50:
UniRef50_O75899
UniGene:
Rn.162814
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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