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83596 BCL2L12

83596

BCL2L12

BCL2 like 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition BCL2 like 12

研究结论

Date Results Publications
2021-03-06 13:29:00 Identification of Two Novel Circular RNAs Deriving from BCL2L12 and Investigation of Their Potential Value as a Molecular Signature in Colorectal Cancer. 33238574
2020-07-25 11:28:00 The previously reported active promoter of BCL2L12 gene differs from the one we described in our study. If this novel BCL2L12 promoter is confirmed to be active in other malignancies, transcripts generated from this region could be considered as new cancer-specific biomarkers. The results of the study contribute to the better understanding of the transcriptional regulation of the BCL2L12 gene. 32387119
2020-06-06 12:17:00 In this study, we explored co-delivery of a TRAIL expressing plasmid (pTRAIL) and complementary small interfering RNAs (siRNAs) (silencing Bcl2-like 12 [BCL2L12] and superoxide dismutase 1 [SOD1]) to improve the response of breast cancer cells against TRAIL therapy 31547718
2019-12-07 11:41:00 BCL2L12 protein expression could be used as a favorable prognostic tissue biomarker in patients with primary advanced-stage LSCC. On the contrary, BCL2 and BAX did not correlate with prognosis in patients with primary LSCC. 31104007
2019-11-02 12:39:00 Increased BCL2L12 v.4 mRNA expression was associated with markers of unfavorable prognosis namely, advanced tumor, ER- (p=0.015)/PR-, Ki-67-positivity and high NPI (Nottingham prognostic index) score 30325729

名称对应

Type IDs
Gene
UniProtKB-ID: B2L12_HUMAN, A0A0X9JFN5_HUMAN, I6LJZ5_HUMAN, I6LJZ7_HUMAN, I6LJZ6_HUMAN, I6LJZ8_HUMAN, I6LJZ9_HUMAN
UniprotKB: Q9HB09, A0A0X9JFN5, I6LJZ5, I6LJZ7, I6LJZ6, I6LJZ8, I6LJZ9
UniParc: UPI000269ADB8, UPI00001267BC, UPI000002A4BB, UPI000269ADB9, UPI000269ADB7, UPI00005B729C, UPI00076E0709, UPI000269ADBA
EMBL: BC007724, CH471177, BC104005, KR820282, FJ868799, FJ911907, BC104004, AF289220, FJ868798, FJ868802, BC104006, AC011495, FJ911906
Ensembl: ENSG00000126453
KO: hsa:83596
Nucleutide sequences
EMBL-CDS: AAH07724.2, AAI04006.1, AAI04007.1, AAG29496.1, AAG29495.1, AAI04005.1, ALU57790.1, ACZ28444.1, ACZ28448.1, EAW52516.1, ACZ28445.1, ACZ28450.1, ACZ28451.1
Gene_ORFName: hCG_21122
Ensembl_TRS: ENST00000246785, ENST00000441864, ENST00000616144, ENST00000619007, ENST00000614495
Protein sequencees
Ensembl_PRO: ENSP00000482218, ENSP00000246785, ENSP00000393803, ENSP00000483272, ENSP00000482154
RefSeq: NP_001269450.1, NP_001372635.1, NP_001035758.1, NP_001269446.1, NP_619580.2, NP_001269445.1, XP_016882835.1, NP_001269448.1, NP_001269449.1
Others
UniRef100: UniRef100_I6LJZ7, UniRef100_Q9HB09, UniRef100_I6LJZ9, UniRef100_I6LJZ8, UniRef100_I6LJZ6, UniRef100_I6LJZ5, UniRef100_A0A0X9JFN5
UniRef90: UniRef90_I6LJZ7, UniRef90_G3QE09, UniRef90_Q9HB09, UniRef90_A0A2I3TKA1
UniRef50: UniRef50_G3QE09, UniRef50_A0A2I3TKA1, UniRef50_Q9D3J3, UniRef50_Q9HB09
UniGene: Hs.289052
CCDS: CCDS46144.1

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