| Type | Description |
|---|---|
| Definition | histone cluster 1 H3 family member b |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:27:00 | Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas. | 32433577 |
| 2019-06-01 10:08:00 | H3K27M mutation in H3F3A occurs exclusively in pediatric high-grade gliomas arising from the midline and presents with varied histomorphological features ranging from low-grade pilomyxoid astrocytoma to highly pleomorphic glioblastoma along | 29063957 |
| 2016-10-22 10:36:00 | This study showed that HIST1H3B (n = 3) across all primary, contiguous, and metastatic tumor sites in all Diffuse intrinsic pontine glioma. | 26727948 |
| 2016-08-27 10:54:00 | Study examined the relationship of K27M mutations in the distinct histone H3 variants (i.e. HIST1H3B and H3F3A) with specific pontine glioma biology | 26399631 |
| 2014-09-06 11:02:00 | These data suggest that adult brainstem gliomas differ from adult supratentorial gliomas. In particular, histone genes (H3F3A (K27M) mutations are frequent in adult brainstem gliomas. | 24242757 |
| Type | IDs |
|---|---|
| Synonymous | H3/l, H3FL |
| Gene |
UniProtKB-ID:
H31_HUMAN
UniprotKB:
P68431
UniParc:
UPI00000003C7
EMBL:
BC148243,
AF531281,
BC099630,
CR541983,
BC096132,
BC096133,
BC066247,
Z80784,
CR542014,
BC148250,
BC067493,
BC096129,
BC143046,
BC067490,
BC067492,
Z83735,
CR541858,
AL031777,
X83550,
BC066884,
M26150,
BC069305,
AF531277,
AF531276,
BC066245,
X00090,
BC066246,
AF531283,
AK311991,
Z83737,
AF531278,
AF531280,
BC096134,
Z80786,
AK316611,
BC096130,
BC127610,
BC069133,
Z98744,
Z46261,
BC096131,
BC069303,
BC069818,
AF531282,
AF531274,
AL009179,
AK313905,
AF531279,
AK314142,
BC031333,
AF531275,
BC067491,
M60746,
Z80785,
BC096128,
CR542011,
X57128
Ensembl:
ENSG00000197409,
ENSG00000277775,
ENSG00000287080,
ENSG00000275714,
ENSG00000274750,
ENSG00000275379,
ENSG00000278828,
ENSG00000273983,
ENSG00000286522,
ENSG00000197153
KO:
hsa:8355,
hsa:8357,
hsa:8356,
hsa:8353,
hsa:8350,
hsa:8354,
hsa:8351,
hsa:8968,
hsa:8352,
hsa:8358
|
| Nucleutide sequences |
EMBL-CDS:
AAN10054.1,
AAH66246.1,
AAH66245.1,
AAN10055.1,
CAG46656.1,
AAH96130.1,
AAI48251.1,
CAA24952.1,
AAA63185.1,
AAN10059.1,
AAN10052.1,
CAB02546.1,
BAG38198.1,
AAN10058.1,
AAH99630.1,
CAA58540.1,
AAH31333.1,
AAH96129.1,
AAH69133.1,
CAA86403.1,
CAA40407.1,
AAI27611.1,
AAH96128.1,
AAH67492.1,
AAH67491.1,
CAB02548.1,
CAG46811.1,
CAG46780.1,
AAH96131.1,
BAG34929.1,
CAG46808.1,
AAH96134.1,
BAG36832.1,
AAN10051.1,
AAN10057.1,
AAA52651.1,
AAN10060.1,
AAI43047.1,
AAI48244.1,
AAN10056.1,
AAH66884.1,
AAH96133.1,
AAN10053.1,
CAB06030.1,
AAH67490.1,
AAH67493.1,
AAH66247.1,
AAH69305.2,
AAH69818.1,
AAH96132.1,
CAB02547.1,
AAH69303.1,
BAG36628.1,
CAB06032.1
Ensembl_TRS:
ENST00000614378,
ENST00000634733,
ENST00000356476,
ENST00000612966,
ENST00000369163,
ENST00000618052,
ENST00000614911,
ENST00000616365,
ENST00000613854,
ENST00000621411,
ENST00000359303
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352252,
ENSP00000484658,
ENSP00000484841,
ENSP00000366999,
ENSP00000489282,
ENSP00000482271,
ENSP00000483283,
ENSP00000484095,
ENSP00000484638,
ENSP00000358160,
ENSP00000480826
RefSeq:
NP_003528.1
|
| Others |
UniRef100:
UniRef100_P68431
UniRef90:
UniRef90_P68431
UniRef50:
UniRef50_P68431
UniGene:
Hs.533292
CCDS:
CCDS4573.1,
CCDS4596.1,
CCDS4600.1,
CCDS4638.1,
CCDS4576.1,
CCDS4570.1,
CCDS4602.1,
CCDS4627.1,
CCDS4590.1,
CCDS4636.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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