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83576 Sort1

83576

Sort1

sortilin 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition sortilin 1

研究结论

Date Results Publications
2018-10-06 11:58:00 A luciferase reporter assay confirmed that SORT1 is the direct target of miR-182. Our study suggests that SORT1 plays a vital role in the development of arterial calcification and is regulated by miR-182. 29196163
2017-10-07 11:19:00 Data suggest that sortilin expression in both gastrocnemius and extensor digitorum longus muscle is down-regulated by 17-18h of fasting/food deprivation; pathological levels of high blood glucose, as in streptozotocin-induced diabetes, do not alter sortilin expression in skeletal muscle; sortilin expression is elevated during differentiation of myocyte cell line or in presence of high concentration of glucose. 27980238
2017-05-27 10:55:00 Reduced sortilin levels associate with lower VLDL apo B secretion. Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells. 27495870
2015-02-14 12:18:00 Compared to the rats in the control group, the rats in the HF group had the expression levels of 12 genes with significant changes, Agrp, Ghrl, and Nr3c1, Apoa4, Cntf, Ghr, IL-1beta, Ins1, Lepr,Sort, Adcyap1r1 and Adrb1. 22715380
2014-09-20 11:51:00 sortilin expression characterizes human atheromatous lesions and rat aortic post-injury neointima, and suggest that sortilin represents an important regulator of proNGF-induced SMC apoptosis and arterial remodeling. 24404198

名称对应

Type IDs
Synonymous Nt3, Nts3
Gene
UniProtKB-ID: SORT_RAT
UniprotKB: O54861
UniParc: UPI000062763C
EMBL: AF019109, AABR03019134, AABR03012291, AABR03012896, AABR03017724, AABR03020083, AF023621
Ensembl: ENSRNOG00000031814
KO: rno:83576
Nucleutide sequences
EMBL-CDS: AAB81864.1, AAC02932.1
Ensembl_TRS: ENSRNOT00000049127
Protein sequencees
Ensembl_PRO: ENSRNOP00000051102
RefSeq: XP_006233258.2, XP_006233256.1, XP_006233257.1, NP_113955.1
Others
UniRef100: UniRef100_O54861
UniRef90: UniRef90_Q6PHU5-2
UniRef50: UniRef50_Q99523
UniGene: Rn.11286

全选

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