| Type | Description |
|---|---|
| Definition | G protein-coupled receptor 101 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:03:00 | GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. | 32958754 |
| 2020-07-25 11:17:00 | findings demonstrate a fundamental role for GPR101 in mediating the leukocyte-directed actions of RvD5n-3 DPA. | 31793912 |
| 2019-10-12 11:02:00 | Duplications of GPR101 gene are associated with X-linked acrogigantism and acromegaly; 924 G>C mutation is associated with sporadic acromegaly | 30711029 |
| 2018-12-22 10:10:00 | Germline or somatic microduplications of the Xq26.3 chromosomal region, invariably involving the GPR101 gene, constitute the genetic defect leading to X-Linked Acrogigantism. GPR101 encodes a class A G protein-coupled receptor that activates the 3',5'-cyclic adenosine monophosphate signaling pathway. | 29678281 |
| 2017-10-28 12:11:00 | This study shows that different GPR101 transcripts exist and that the brain is the major site of GPR101 expression across different species, although divergent species- and temporal-specific expression patterns are evident. These findings suggest an important role for GPR101 in brain and pituitary development and likely reflect the very different growth, development and maturation patterns among species. | 27282544 |
| Type | IDs |
|---|---|
| Synonymous | GPCR6, PAGH2, PITA2 |
| Gene |
UniProtKB-ID:
GP101_HUMAN
UniprotKB:
Q96P66
UniParc:
UPI000003BCCD
EMBL:
CH471150,
AF411115,
AB065937,
BC069439,
AB083588,
AL390879
Ensembl:
ENSG00000165370
KO:
hsa:83550
|
| Nucleutide sequences |
EMBL-CDS:
BAC06152.1,
EAW88450.1,
AAL26486.1,
BAB89301.1,
AAH69439.1
Ensembl_TRS:
ENST00000298110,
ENST00000651716
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000498972,
ENSP00000298110
RefSeq:
NP_473362.1
|
| Others |
UniRef100:
UniRef100_Q96P66
UniRef90:
UniRef90_Q96P66
UniRef50:
UniRef50_Q96P66
UniGene:
Hs.350569
CCDS:
CCDS14662.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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