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83549 UCK1

83549

UCK1

uridine-cytidine kinase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition uridine-cytidine kinase 1

研究结论

Date Results Publications
2019-02-02 10:30:00 Knockdown of endogenous UCK2 as well as overexpression of UCK1 resulted in decreased metabolism of uridine and cytidine and protected neuroblastoma cells from 3-deazauridine-induced toxicity. Subcellular localization studies showed that UCK1-GFP and UCK2-GFP were localized in the cell nucleus and cytosol, respectively. 27239701
2018-07-23 13:18:00 Results from a study on gene expression variability markers in early-stage human embryos shows that UCK1 is a putative expression variability marker for the 3-day, 8-cell embryo stage. 26288249
2017-03-18 12:41:00 UCK1 and 2 are both expressed in several neuroblastoma cell lines, including four MYCN single copy cell lines and five MYCN amplified cell lines 27906629
2010-01-21 00:00:00 ribavirin is a potential substrate of UCK-1, and RMP formed could be chemically coupled to AsOR to form a conjugate for liver specific targeting. 18080217

名称对应

Type IDs
Synonymous URK1
Gene
UniProtKB-ID: UCK1_HUMAN, A0A0S2Z5Y6_HUMAN, A0A024R8E7_HUMAN
UniprotKB: Q9HA47, A0A0S2Z5Y6, A0A024R8E7
UniParc: UPI00004A2DB7, UPI0007205389, UPI000004B291, UPI000013CDA8, UPI0000210D0B
EMBL: BC091495, AF125106, CH471090, KU178794, AK295471, KU178796, AK022317, BC015547, AF237290, AF254133, AL358781, CR457281
Ensembl: ENSG00000130717
KO: hsa:83549
Nucleutide sequences
EMBL-CDS: AAK49122.1, BAB14010.1, AAK28324.1, AAL75943.1, CAG33562.1, AAH15547.1, EAW87983.1, BAG58400.1, AAH91495.1, ALQ34254.1, ALQ34252.1, EAW87984.1
Gene_ORFName: hCG_29237
Ensembl_TRS: ENST00000372215, ENST00000372208, ENST00000372210, ENST00000372211
Protein sequencees
Ensembl_PRO: ENSP00000361282, ENSP00000361284, ENSP00000361289, ENSP00000361285
RefSeq: XP_005272281.1, NP_113620.1, NP_001248379.1, NP_001248380.1, NP_001129426.1, NP_001305448.1
Others
UniRef100: UniRef100_A0A024R8E7, UniRef100_A0A0S2Z5Y6, UniRef100_Q9HA47
UniRef90: UniRef90_Q4R4K2, UniRef90_A0A024R8E7, UniRef90_Q9HA47
UniRef50: UniRef50_Q9HA47, UniRef50_Q4R4K2, UniRef50_A0A383ZBU2
UniGene: Hs.9597
CCDS: CCDS59152.1, CCDS48046.1, CCDS59151.1, CCDS6944.1

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