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83547 RILP

83547

RILP

Rab interacting lysosomal protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rab interacting lysosomal protein

研究结论

Date Results Publications
2019-03-02 12:02:00 structural and biochemical investigation of the Rab7-ORP1L interaction revealed architecture that leaves the canonical effector-interacting switch regions available for RILP binding and thus allows formation of the ORP1L-Rab7-RILP tripartite complex. 30012887
2019-01-05 10:04:00 Caspase-1 regulates cellular trafficking via cleavage of the Rab7 adaptor protein RILP in cultured neoplastic epithelial cells has been reported. 30100068
2018-03-31 11:48:00 Hepatitis C virus (HCV) modifies cellular trafficking by cleaving Rab interacting lysosomal protein (RILP), which serves to redirect ras-related protein Rab-7 (Rab7)-containing vesicles to a kinesin-dependent trafficking mode promoting virion secretion. 27791088
2016-06-28 11:31:00 RILP suppresses the invasion of breast cancer cells by interacting with RalGDS to inhibit its guanine nucleotide exchange factor activity for RalA. 26469971
2016-05-21 12:42:00 RILP regulates vacuolar ATPase through interaction with the V1G1 subunit 26180254

名称对应

Type IDs
Synonymous PP10141
Gene
UniProtKB-ID: RILP_HUMAN
UniprotKB: Q96NA2
UniParc: UPI000022EE38, UPI0000073C49
EMBL: AK314767, BC004961, BC031621, AF370391, AK055755, AJ278711, AJ404317
Ensembl: ENSG00000167705, ENSG00000274145
KO: hsa:83547
Nucleutide sequences
EMBL-CDS: BAB71003.1, AAH31621.1, BAG37305.1, CAC82174.1, AAQ15227.1, AAH04961.1, CAC33443.1
Gene_ORFName: PP10141
Ensembl_TRS: ENST00000301336, ENST00000622136
Protein sequencees
Ensembl_PRO: ENSP00000301336, ENSP00000481849
RefSeq: XP_005256868.1, XP_016880684.1, NP_113618.2
Others
UniRef100: UniRef100_Q96NA2
UniRef90: UniRef90_Q96NA2
UniRef50: UniRef50_Q96NA2
UniGene: Hs.534497
CCDS: CCDS11009.1

全选

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研究热度

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