| Type | Description |
|---|---|
| Definition | solute carrier family 22 member 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:05:00 | Atorvastatin attenuates obese-induced kidney injury and impaired renal organic anion transporter 3 function through inhibition of oxidative stress and inflammation. | 32101757 |
| 2019-08-31 10:26:00 | Data suggest that a remote sensing and signaling system between gut and kidney by which probiotic might facilitate renal handling of gut microbiota products through the improvement of organic anion transporter 3 (Oat3) function. | 29980603 |
| 2019-04-06 11:23:00 | Study results indicate that Oat1 and Oat3 at the blood-arachnoid barrier provide a distinct clearance pathway of organic anion drugs from cerebrospinal fluid independently of choroid plexus. | 29436232 |
| 2018-07-14 10:43:00 | These results indicated that OAT1 and OAT3 played crucial roles: (1) in determining baseline levels of blood BP by excluding endogenous BP through the urine, (2) in the rapid distribution to organs of exogenous BH4 and the exclusion to urine of a BH4 excess, particularly when BH4 was administered, and (3) in scavenging blood BH2 by cellular uptake as the gateway to the salvage pathway of BH4, which reduces BH2 back to BH4 | 28534121 |
| 2016-04-16 11:58:00 | Suggest OCT3 as possible norepinephrine uptake transporter in perivascular adipose tissue. | 26432838 |
| Type | IDs |
|---|---|
| Synonymous | OCT3, Oat3, Roct |
| Gene |
UniProtKB-ID:
S22A8_RAT
UniprotKB:
Q9R1U7
UniParc:
UPI00000E877B
EMBL:
AB017446,
BC081777
KO:
rno:83500
|
| Nucleutide sequences |
EMBL-CDS:
AAH81777.1,
BAA82552.1
|
| Protein sequencees |
RefSeq:
XP_008758465.1,
NP_112622.1
|
| Others |
UniRef100:
UniRef100_Q9R1U7
UniRef90:
UniRef90_Q9R1U7
UniRef50:
UniRef50_Q9R1U7
UniGene:
Rn.23348
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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