| Type | Description |
|---|---|
| Definition | histone cluster 2 H2B family member e |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:35:00 | Nucleotide variation in histone H2BL drives crossalk of histone modification and promotes tumour cell proliferation by upregulating c-Myc. | 33515561 |
| 2019-08-17 10:05:00 | hese results suggest that TRAIP is a novel regulator of H2B monoubiquitination in DNA damage response and cancer development in lung adenocarcinoma. | 30942468 |
| 2018-02-10 10:30:00 | we found an excess of mutations in genes encoding histone H2A and H2B, as well as significant amplification of the segment of chromosome 6p harboring the histone gene cluster containing these genes.We also found frequent deletions of the genes TP53 and MBD3 (a member with CHD4 of the nucleosome remodeling deacetylase complex). | 27791010 |
| 2017-10-28 10:45:00 | Findings uncover a novel function of let-7 miRNAs as regulators of H2B ubiquitylation, suggesting an additional mechanism whereby these miRNAs can exert their tumor-suppressive effects. | 28604753 |
| 2017-08-05 10:10:00 | Within the nucleus, catalytic activity maintains the Ser536 phosphorylation on the p65 subunit of NF-kappaB (also known as RelA) and can directly influence chromatin accessibility at transcriptional memory genes by regulating H2B deposition. | 27149922 |
| Type | IDs |
|---|---|
| Synonymous | GL105, H2B, H2B.1, H2BFQ, H2BGL105, H2BQ |
| Gene |
UniProtKB-ID:
H2B2E_HUMAN
UniprotKB:
Q16778
UniParc:
UPI0000000C6F
EMBL:
BC005827,
BC098289,
AY131979,
BC107084,
BC069193,
AL591493,
X57985,
BC096121,
M60756,
BC107085,
BC098112,
CR541895,
CH471121,
AK289725
Ensembl:
ENSG00000184678
KO:
hsa:8349
|
| Nucleutide sequences |
EMBL-CDS:
AAH69193.1,
AAH05827.1,
AAH98289.1,
AAN59961.1,
AAH96121.1,
BAF82414.1,
CAA41051.1,
CAG46693.1,
AAH98112.1,
AAA63192.1,
EAW53605.1,
AAI07086.1,
CAI12568.1,
AAI07085.1
Ensembl_TRS:
ENST00000369155
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358151
RefSeq:
NP_003519.1
|
| Others |
UniRef100:
UniRef100_Q6FI13
UniRef90:
UniRef90_Q6FI13
UniRef50:
UniRef50_Q6FI13
UniGene:
Hs.2178
CCDS:
CCDS936.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员