| Type | Description |
|---|---|
| Definition | Moloney leukemia virus 10-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:34:00 | The N-terminus of MOV10 also leads to increased RGG box-dependent binding to the SC1 RNA G-Quadruplex and is required for outgrowth of neurites. Lastly, we showed that FMRP has a global role in miRNA-mediated translational regulation by recruiting AGO2 to a large subset of RNAs in mouse brain. | 31740951 |
| 2019-11-09 12:10:00 | The data expand the landscape of MOV10 function and highlight a previously unidentified role initiated from the nucleus, suggesting that MOV10 is a versatile RNA-binding protein involved in a broader RNA regulatory network. | 31088452 |
| 2017-08-23 10:40:00 | Conditional inactivation of the putative RNA helicase Mov10l1 in mouse spermatocytes produces a specific loss of pachytene piRNAs, significant accumulation of pachytene piRNA precursor transcripts, and unusual polar conglomeration of Piwi proteins with mitochondria. Mov10l1 is required for pachytene piRNA biogenesis. | 23166510 |
| 2016-09-26 17:13:00 | Mutations in the conserved ATP hydrolysis motif of MOV10L1 block piRNA biogenesis and result in male sterility. | 27655786 |
| 2015-10-10 10:42:00 | MOV10L1 RNA helicase activity promotes unwinding and funneling of the single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing | 25762440 |
| Type | IDs |
|---|---|
| Synonymous | CHAMP, Csm |
| Gene |
UniProtKB-ID:
M10L1_MOUSE,
G3X8T0_MOUSE,
D3YWG8_MOUSE
UniprotKB:
Q99MV5,
G3X8T0,
D3YWG8
UniParc:
UPI00015AA095,
UPI0000564B7A,
UPI000002AD80,
UPI0000027F72,
UPI00001AA1E8
EMBL:
KY774831,
AC113069,
AK084786,
AF285587,
AC119959,
AF340211,
AY303754
Ensembl:
ENSMUSG00000015365
KO:
mmu:83456
|
| Nucleutide sequences |
EMBL-CDS:
AAK77049.1,
AAP60176.1,
BAC39279.1,
AAK31966.1,
AVN68394.1
Ensembl_TRS:
ENSMUST00000015509,
ENSMUST00000146993
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000015509,
ENSMUSP00000118437
RefSeq:
XP_006521620.1,
XP_006521619.1,
NP_112550.2
|
| Others |
UniRef100:
UniRef100_Q99MV5,
UniRef100_D3YWG8
UniRef90:
UniRef90_Q99MV5
UniRef50:
UniRef50_Q99MV5
UniGene:
Mm.358791
CCDS:
CCDS27737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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