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83416 FCRL5

83416

FCRL5

Fc receptor like 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition Fc receptor like 5

研究结论

Date Results Publications
2019-09-07 11:57:00 FCRL5 has dual signaling capacity, while CD21 co-engagement serves as molecular switch, converting FCRL5 from a negative to a positive co-receptor; in tissues, B cells that co-express FCRL5 and CD21 could robustly respond to IgG immune complexes loaded with C3 fragments 30107486
2019-05-11 13:07:00 This study identified novel Single nucleotide polymorphism in FCRL3 and FCRL5 significantly associated with the risk for asthma with comorbid allergic rhinitis in the Chinese population 30771554
2017-12-02 11:01:00 based on FCRL5 binding, we can discern distinct changes in the IgG2 molecule, including the disulfide isoform structure and charge variants related to deamidation. Since both IgG2 deamidation and conversion of disulfide isoforms occur in vivo, these findings elucidate the biological FCRL5 ligand. 29101848
2017-09-09 10:18:00 we found that FCRL5 expression is induced specifically upon BCR stimulation and dissected the molecular mechanism 27065451
2017-07-29 10:09:00 this study revealed that the FCRL5+ tissue-like memory subset responds poorly to multiple stimuli compared with the FCRL5- subset, as reflected by reduced calcium mobilization and blunted cell proliferation 27076679

名称对应

Type IDs
Synonymous BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820
Gene
UniProtKB-ID: FCRL5_HUMAN
UniprotKB: Q96RD9
UniParc: UPI0000458908, UPI0000119B9C, UPI0000204ADE, UPI0000049DED, UPI0000458907
EMBL: AF397453, BC101067, AF343665, AL135929, AF369794, AL353899, EF064730, AY358085, AL834187, BC101066, AF343662, AF343664, AF343663, BC101069
Ensembl: ENSG00000143297
KO: hsa:83416
Nucleutide sequences
EMBL-CDS: AAI01070.1, AAK50059.2, AAK93971.1, AAK31326.1, AAI01067.1, AAK31328.1, AAQ88452.1, ABK41913.1, AAI01068.1, AAK31325.1, CAH56486.1, AAK31327.1
Gene_ORFName: UNQ503/PRO820
Ensembl_TRS: ENST00000368190, ENST00000361835, ENST00000368189
Protein sequencees
Ensembl_PRO: ENSP00000354691, ENSP00000357173, ENSP00000357172
RefSeq: XP_011508335.1, XP_011508333.1, NP_001182317.1, XP_011508332.1, XP_011508334.1, NP_112571.2
Others
UniRef100: UniRef100_Q96RD9
UniRef90: UniRef90_Q96RD9
UniRef50: UniRef50_Q96RD9
UniGene: Hs.415950
CCDS: CCDS1165.1

全选

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