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83396 Glis2

83396

Glis2

GLIS family zinc finger 2

protein-coding

Mus musculus

基因描述

Type Description
Definition GLIS family zinc finger 2

研究结论

Date Results Publications
2019-05-18 12:03:00 Ring1A/B regulate and maintain AML stem cells in part by repressing Glis2 expression, which promotes their differentiation. 29371181
2017-09-30 10:27:00 Kif3a is required for cell cycle regulation and the DNA damage response, whereas cell senescence is significantly enhanced in Glis2 null cells. 27181777
2011-03-26 10:46:00 Glis2 can function as a transcriptional activator and that post-translational modification within its DNA-binding domain can regulate its transcriptional activity 21127075
2010-01-21 00:00:00 Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and repressor functions 11741991
2010-01-21 00:00:00 Deficiency in Glis2 expression leads to tubular atrophy & progressive fibrosis, similar to nephronophthisis, that ultimately results in renal failure. Glis2 plays a critical role in the maintenance of normal kidney architecture and functions. 18227149

名称对应

Type IDs
Synonymous Gli5, Klf16, Nkl
Gene
UniProtKB-ID: GLIS2_MOUSE
UniprotKB: Q8VDL9
UniParc: UPI000002131C
EMBL: BC021517, AF249340, AF325913, AF336135
Ensembl: ENSMUSG00000014303
KO: mmu:83396
Nucleutide sequences
EMBL-CDS: AAL93213.1, AAK28410.1, AAH21517.1, AAK00953.1
Ensembl_TRS: ENSMUST00000014447
Protein sequencees
Ensembl_PRO: ENSMUSP00000014447
RefSeq: XP_011244352.1, XP_036016078.1, XP_036016079.1, XP_011244350.1, XP_036016080.1, XP_006522831.1, XP_011244351.1, NP_112461.2, XP_036016081.1
Others
UniRef100: UniRef100_Q8VDL9
UniRef90: UniRef90_Q8VDL9
UniRef50: UniRef50_Q8VDL9
UniGene: Mm.134072
CCDS: CCDS27920.1

全选

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