| Type | Description |
|---|---|
| Definition | sialic acid binding Ig-like lectin E |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:27:00 | Polysialic acid and Siglec-E orchestrate negative feedback regulation of microglia activation. | 32725371 |
| 2020-10-03 12:56:00 | Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-kappaB pathway. | 31918287 |
| 2017-09-30 13:38:00 | The Siglec-E-deficient dendritic cells were defective for TRIF-mediated IFN-beta production in response to E. coli infection. | 27619995 |
| 2017-07-22 13:12:00 | This study demonstrated that virulent parasite Leishmania donovani (AG83+Sias) establish a unique sialic acids-mediated binding and subsequent phagocytosis in the host cell through the selective exploitation of siglec-1. | 27494323 |
| 2017-06-03 12:18:00 | new data relating to the structure and function of Siglec-E, the major CD33-related Siglec expressed on mouse neutrophils, monocytes, macrophages, and dendritic cells. | 27920204 |
| Type | IDs |
|---|---|
| Synonymous | Cd170, Siglec12, Siglec5, Siglec9, Siglecl1, mSiglec-E |
| Gene |
UniProtKB-ID:
SIG12_MOUSE
UniprotKB:
Q91Y57
UniParc:
UPI00000234E6
EMBL:
AF329269,
AF317298,
AC151989
Ensembl:
ENSMUSG00000030474
KO:
mmu:83382
|
| Nucleutide sequences |
EMBL-CDS:
AAK49917.1,
AAG38598.1
Ensembl_TRS:
ENSMUST00000032667
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032667
RefSeq:
XP_006541383.1,
XP_006541384.1,
NP_112458.2,
XP_006541381.1,
XP_006541382.1
|
| Others |
UniRef100:
UniRef100_Q91Y57
UniRef90:
UniRef90_Q91Y57
UniRef50:
UniRef50_Q91Y57
UniGene:
Mm.157702
CCDS:
CCDS21178.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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