| Type | Description |
|---|---|
| Definition | histone cluster 2 H2A family member c |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 10:30:00 | we found an excess of mutations in genes encoding histone H2A and H2B, as well as significant amplification of the segment of chromosome 6p harboring the histone gene cluster containing these genes.We also found frequent deletions of the genes TP53 and MBD3 (a member with CHD4 of the nucleosome remodeling deacetylase complex). | 27791010 |
| 2015-08-29 10:49:00 | Glycated-H2A histone is better bound by serum anti-DNA autoantibodies in systemic lupus erythematosus patients, and could be a likely trigger for the disease. | 25065453 |
| 2012-06-09 10:26:00 | Our results provide mechanistic insight into how post-translational modification of H2A at the site of a photolesion initiates the repair process and directly affects the stability of the human genome. | 22334663 |
| 2011-08-20 10:49:00 | Aurora-B-dependent phosphorylation of condensin promotes its association with histone H2A and H2A.Z, which we identify as conserved chromatin 'receptors' of condensin | 21633354 |
| 2011-08-06 11:13:00 | L3MBTL2-specific resulted in increased expression of target genes that exhibited a significant reduction in H2A lysine 119 monoubiquitination. | 21596310 |
| Type | IDs |
|---|---|
| Synonymous | H2A, H2A-GL101, H2A/q, H2AFQ |
| Gene |
UniProtKB-ID:
H2A2C_HUMAN
UniprotKB:
Q16777
UniParc:
UPI000007478F
EMBL:
X57985,
AL591493,
BC060324,
AY648852,
AY131973
Ensembl:
ENSG00000184260
KO:
hsa:8338
|
| Nucleutide sequences |
EMBL-CDS:
AAT68255.1,
CAA41050.1,
AAH60324.1,
CAI12569.1,
AAN59959.1
Ensembl_TRS:
ENST00000331380
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000332194
RefSeq:
NP_003508.1
|
| Others |
UniRef100:
UniRef100_Q16777
UniRef90:
UniRef90_Q16777
UniRef50:
UniRef50_Q16777
UniGene:
Hs.408067
CCDS:
CCDS937.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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