| Type | Description |
|---|---|
| Definition | klotho beta |
| Date | Results | Publications |
|---|---|---|
| 2019-08-31 12:03:00 | Study demonstrated, for the first time, that betaKlotho was strongly expressed in cells infiltrating the lesional dermis of psoriatic patients compared with control or atopic dermatitis patients and in cells infiltrating the skin of imiquimod-treated mice than in untreated mice. | 30302794 |
| 2019-08-31 11:08:00 | Klb(-/-) mice present permanent growth restriction independent of adiposity and energy balance. Klb(-/-) mice also exhibit few changes in carbohydrate metabolism, combining normal gluco-tolerance, insulin sensitivity, and fasting response with increased gluconeogenic capacity and decreased glycogen mobilization. Livers of Klb(-/-) mice have pathologic features, including a proinflammatory status and initiation of fibrosis | 29944388 |
| 2018-12-22 12:23:00 | Downregulation of beta-klotho expression is not the major mechanism of impaired FGF21 signaling in white adipose tissue. | 28580290 |
| 2017-07-22 10:41:00 | liver FGF21-betaKlotho pathway sufficient and necessary to repress mTOR/S6K activity | 26926384 |
| 2017-06-24 11:53:00 | The study supports a pro-adipogenic role for betaKlotho in skeletal muscle fibro/adipogenesis and calls for further research on involvement of the FGF-FGFR-betaKlotho axis in the fibro/adipogenic infiltration associated with functional deterioration of skeletal muscle in aging and muscular dystrophy. | 26881702 |
| Type | IDs |
|---|---|
| Synonymous | AV071179, betaKlotho |
| Gene |
UniProtKB-ID:
KLOTB_MOUSE
UniprotKB:
Q99N32
UniParc:
UPI0000027F4B,
UPI000002311E
EMBL:
BC138010,
BC138008,
AF165170,
AF165171,
AF178429
Ensembl:
ENSMUSG00000029195
KO:
mmu:83379
|
| Nucleutide sequences |
EMBL-CDS:
AAK28705.1,
AAL01648.1,
AAI38009.1,
AAI38011.1,
AAK28704.1
Ensembl_TRS:
ENSMUST00000031096
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031096
RefSeq:
XP_006504267.1,
NP_112457.1
|
| Others |
UniRef100:
UniRef100_Q99N32
UniRef90:
UniRef90_Q99N32
UniRef50:
UniRef50_Q99N32
UniGene:
Mm.45274
CCDS:
CCDS19306.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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