| Type | Description |
|---|---|
| Definition | histone cluster 2 H2A family member a3 |
| Date | Results | Publications |
|---|---|---|
| 2012-11-24 11:00:00 | Ubiquitin-dependent signaling during the DNA damage response (DDR) to double-strand breaks is initiated by two E3 ligases, RNF8 and RNF168, targeting histone H2A and H2AX. Study shows that ubiquitin chains per se are insufficient for signaling, but RNF168 target ubiquitination is required for DDR damage. | 22980979 |
| Type | IDs |
|---|---|
| Synonymous | H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA |
| Gene |
UniProtKB-ID:
H2A2A_HUMAN
UniprotKB:
Q6FI13
UniParc:
UPI00000006DA
EMBL:
BC096739,
L19779,
CR541872,
AL591493,
BC098171,
CH878687,
AK312163,
CR536525,
BC096705,
AY131971
Ensembl:
ENSG00000272196,
ENSG00000203812
KO:
hsa:8337,
hsa:723790
|
| Nucleutide sequences |
EMBL-CDS:
BAG35097.1,
CAI12565.1,
AAH98171.1,
CAG38762.1,
EAW50859.1,
AAN59957.1,
CAI12562.1,
AAH96705.1,
AAC24465.1,
CAG46670.1,
AAH96739.1
Ensembl_TRS:
ENST00000607355,
ENST00000369159
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000475814,
ENSP00000358155
RefSeq:
NP_003507.1
|
| Others |
UniRef100:
UniRef100_Q6FI13
UniRef90:
UniRef90_Q6FI13
UniRef50:
UniRef50_Q6FI13
UniGene:
Hs.530461
CCDS:
CCDS934.1,
CCDS30849.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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