Type | Description |
---|---|
Definition | capping actin protein of muscle Z-line subunit beta |
Date | Results | Publications |
---|---|---|
2018-07-21 11:28:00 | CAPZB controls spindle orientation independently of its classical role in the actin cytoskeleton by regulating the assembly, stability, and motor activity of the dynein/dynactin complex at the cell cortex, as well as the dynamics of mitotic microtubules. | 28803871 |
2018-03-10 11:02:00 | replication confirmed at genome-wide significance the association of loci at FOXE1 with hypothyroidism, and PDE8B, CAPZB and PDE10A with serum TSH. A total of 12 SNPs seemed to explain nearly 7% of the serum TSH variation | 28727628 |
2018-02-24 11:06:00 | At each step during spermatogenesis, the cellular localization of hCPbeta3 changed dynamically. In spermatogonia, hCPbeta3 showed a slight signal in cytoplasm. hCPbeta3 expression was conspicuous mainly from spermatocytes, and hCPbeta3 localization dynamically migrated from cytoplasm to the acrosomal cap and acrosome. In mature spermatozoa, hCPbeta3 accumulated in the postacrosomal region and less so at the midpiece of... | 28104696 |
2017-01-28 11:08:00 | A subject with micrognathia, cleft palate and hypotonia harbored a de novo, balanced chromosomal translocation that disrupts the CAPZB gene. The function of capzb was analyzed in the zebrafish model. | 26758871 |
2016-12-17 10:07:00 | CAPZB is involved in tumor progression in cases of epithelioid sarcoma (EpiS), irrespective of the INI1 expression, and may be a potential therapeutic target. The paradoxical relationship between the tumor suppressor INI1 and the oncoprotein CAPZB in the pathogenesis of EpiS remains to be clarified | 26965049 |
Type | IDs |
---|---|
Synonymous | CAPB, CAPPB, CAPZ |
Gene |
UniProtKB-ID:
CAPZB_HUMAN,
B1AK88_HUMAN,
A0A384MR50_HUMAN,
B4DWA6_HUMAN,
B1AK85_HUMAN,
Q7L4N0_HUMAN
UniprotKB:
P47756,
B1AK88,
A0A384MR50,
B4DWA6,
B1AK85,
Q7L4N0
UniParc:
UPI0000028D73,
UPI0000458977,
UPI0000458978,
UPI0000374749,
UPI0000126EDB,
UPI00017A827F
EMBL:
AK301442,
AL359199,
AL445163,
BT019470,
CH471134,
KF495883,
U03271,
GQ900984,
BT019471,
BC109241,
BC109242,
BC107752,
AK125085,
AL035413,
BC024601,
BC008095
Ensembl:
ENSG00000077549
KO:
hsa:832
|
Nucleutide sequences |
EMBL-CDS:
AAH24601.1,
AAA87395.1,
AAV38278.1,
AAI09243.1,
EAW94890.1,
AAI07753.1,
AAV38277.1,
AAI09242.1,
EAW94891.1,
ADO22501.1,
BAG62968.1,
BAG54137.1,
AAH08095.2
Gene_ORFName:
hCG_41078
Ensembl_TRS:
ENST00000375142,
ENST00000264202,
ENST00000674432,
ENST00000433834,
ENST00000264203
|
Protein sequencees |
Ensembl_PRO:
ENSP00000264202,
ENSP00000501528,
ENSP00000364284,
ENSP00000401010,
ENSP00000264203
RefSeq:
NP_004921.1,
NP_001269091.1,
XP_016857918.1,
XP_024305865.1,
NP_001300861.1,
XP_006711001.1,
NP_001193469.1,
XP_016857917.1,
XP_024305864.1,
XP_016857919.1,
XP_011540532.1,
XP_011540530.1,
NP_001193470.1,
XP_011540531.1
|
Others |
UniRef100:
UniRef100_B1AK85,
UniRef100_B4DWA6,
UniRef100_Q5R507,
UniRef100_A2AMW0,
UniRef100_B1AK88,
UniRef100_P47756
UniRef90:
UniRef90_A0A2K5TMG9,
UniRef90_P79136,
UniRef90_A0A673UL98,
UniRef90_B1AK85,
UniRef90_Q5R507,
UniRef90_P47757
UniRef50:
UniRef50_P14315,
UniRef50_Q7SXP1,
UniRef50_P47757
UniGene:
Hs.432760
CCDS:
CCDS55579.1,
CCDS41277.1
|
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