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8318 CDC45

8318

CDC45

cell division cycle 45

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell division cycle 45

研究结论

Date Results Publications
2021-01-16 15:59:00 Pathogenic variants in CDC45 on the remaining allele in patients with a chromosome 22q11.2 deletion result in a novel autosomal recessive condition. 31474763
2020-06-13 12:17:00 Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 31562245
2020-05-09 11:32:00 RYBP suppresses esophageal squamous cell carcinoma proliferation by downregulating CDC6 and CDC45, thus inhibiting the G1-S transition 32209426
2020-04-18 12:40:00 High level of DNAJA1 predicted poor prognosis for colorectal cancer (CRC) patients. Its expression was highly linked with E2F1 and CDC45 in CRC tissues. More importantly, KNK437 significantly suppressed the growth of DNAJA1 expressing tumor in vivo 31477839
2019-12-21 10:48:00 expression knockdown of CDC45 inhibited non-small cell lung cancer cell proliferation. 30887286

名称对应

Type IDs
Synonymous CDC45L, CDC45L2, MGORS7, PORC-PI-1
Gene
UniProtKB-ID: CDC45_HUMAN
UniprotKB: O75419
UniParc: UPI0000D4C86A, UPI0000000C75, UPI000042153E
EMBL: AK293123, CT841513, BC010022, BT006792, AC000087, AC000088, AK293338, AF053074, AF081535, AC000082, CH471176, AJ223728, BC006232, AY358971, AF062495, AY572790
Ensembl: ENSG00000093009
KO: hsa:8318
Nucleutide sequences
EMBL-CDS: AAP35438.1, AAC67521.1, BAG56675.1, AAH10022.1, BAG56854.1, AAC27289.1, AAS66985.1, CAJ86443.1, AAQ89330.1, AAD08998.1, EAX03036.1, AAH06232.1, CAA11530.1
Gene_ORFName: UNQ374/PRO710
Ensembl_TRS: ENST00000263201, ENST00000437685, ENST00000404724
Protein sequencees
Ensembl_PRO: ENSP00000263201, ENSP00000384978, ENSP00000405726
RefSeq: XP_011528720.1, NP_001171482.1, NP_001171481.1, XP_016884456.1, XP_024308045.1, NP_001356220.1, XP_011528718.1, XP_016884455.1, NP_003495.1, XP_011528719.1
Others
UniRef100: UniRef100_O75419
UniRef90: UniRef90_O75419
UniRef50: UniRef50_O75419
UniGene: Hs.474217, Hs.742418
CCDS: CCDS13762.1, CCDS54499.1, CCDS54500.1

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