GAD - glutamate decarboxylase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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831599 GAD

基因描述

Type	Description
Definition	glutamate decarboxylase

研究结论

Date	Results	Publications
2016-06-28 10:52:00	mutations in the two lobes affect GAD1 activation in similar ways and only intact AtCaM1 can fully activate GAD1. Taken together, our data provide new insights into the CaM lobes role in interactions between CaM and plant GAD.	26708477
2010-01-21 00:00:00	Insertion mutants of GAD1 revealed that GABA levels in roots were drastically reduced compared with those in the wild type.	15604684
2010-01-21 00:00:00	Antibody titers to this enzyme identify two subgroups of patients with adult-onset autoimmune diabetes having distinct clinical, autoimmune, and genetic features.	17392553
2010-01-21 00:00:00	Calmodulin activates Gad1 in a unique way by relieving two C-terminal autoinhibition domains of adjacent active sites, forming a 393 kDa Gad1-calmodulin complex with an unusual 1:3 stoichiometry.	19580813

名称对应

Type	IDs
Synonymous	GAD1, GLUTAMATE DECARBOXYLASE, GLUTAMATE DECARBOXYLASE 1, MKP11.30, MKP11_30, glutamate decarboxylase
Gene	UniProtKB-ID: DCE1_ARATH, A0A5S9Y4Y1_ARATH UniprotKB: Q42521, A0A5S9Y4Y1 UniParc: UPI0000001AFC EMBL: CP002688, CACSHJ010000096, AY094464, CACRSJ010000110, AB005238, BT001047, U10034 EnsemblGenome: AT5G17330 KO: ath:AT5G17330
Nucleutide sequences	EMBL-CDS: AAN46801.1, AAM19834.1, AED92414.1, BAB10520.1, AAA93132.1, VYS67110.1, CAA0403192.1 Gene_ORFName: MKP11_18, MKP11.30, AN1_LOCUS22511, C24_LOCUS22401 EnsemblGenome_TRS: AT5G17330.1
Protein sequencees	EnsemblGenome_PRO: AT5G17330.1 RefSeq: NP_197235.1
Others	UniRef100: UniRef100_Q42521 UniRef90: UniRef90_Q42521 UniRef50: UniRef50_Q42521 UniGene: At.25228

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
26708477	Biochemical and biophysical characterization of a plant calmodulin: Role of the N- and C-lobes in calcium binding, conformational change, and target interaction. Biochim. Biophys. Acta Alessandra Astegno , Valentina La Verde , Valerio Marino , Daniele Dell'Orco , Paola Dominici	2016-03-01	-
25614413	Functional roles of the hexamer organization of plant glutamate decarboxylase. Biochim. Biophys. Acta Alessandra Astegno , Guido Capitani , Paola Dominici	2015-09-01	GAD
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21166475	Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. J. Proteome Res. Jun Ito , Tanveer S Batth , Christopher J Petzold , Alyssa M Redding-Johanson , Aindrila Mukhopadhyay , Robert Verboom , Etienne H Meyer , A Harvey Millar , Joshua L Heazlewood	2011-04-01	AT3G08943, AT3G08947, AT3G07030, AT3G42170, AT4G22285, AT1G24800, AT1G25055, AT1G24881, AT1G25211, AT2G01250, AT2G01690, GSTZ1, AT2G02400, AL6, CAND1, UBC2, GEK1, AT2G03820, CR88, AT2G04390, AT2G04400, AT2G04520, AT2G05220, ACO3, AT2G05920, HEN2, PFD1, AT2G07360, AT2G09990, ABH1, DRP3B, PIP, UGT73B4, NIR1, SQN, AT2G15860, HB1, THY-1, PAP10, MCM4, AT2G16485, ASE1, ROC3, MSI2, UBC23, AT2G16940, TRN1, DSK2, AT2G17280, CPK6, AT2G17360, NTRA, AT2G17930, ATSLY1, EMB2296, PIN1AT, AT2G18110, AT2G18220, COAD, TPS11, AT2G18740, NAP1;2, FVE, CDA1, PRMT1A, PRF1, AT2G20140, CLASP, RPN1A, AT2G20760, AT2G21130, TIM, AT2G21250, UFD1, AT2G21390, CCR2, AT2G22125, AAT, AT2G22420, GEM, SNRK2.9, AT2G23070, PAB4, AT2G23820, SNRNP-G, eIFiso4G2, AT2G24190, AT2G24200, AT2G24590, MAPR2, AT2G25670, AT2G25970, SEH, FUS12, PAG1, CAM5, AGO4, SE, AAO3
21094157	14-3-3 proteins fine-tune plant nutrient metabolism. FEBS Lett. Ryoung Shin , Joseph M Jez , Amarjit Basra , Bei Zhang , Daniel P Schachtman	2011-01-03	ArthMp038, LCR16, LCR46, ArthMp095, PAP1, RPI2, RGA1, BRL2, LCR72, ZAP1, AT2G07750, NIR1, ROC3, AT2G18140, GGPS4, PHYB, FRK1, AT2G19490, AT2G20030, AT2G20780, AT2G21130, RER1B, SR1, AT2G22420, HB6, HAT9, AT2G22950, GH3.3, CNGC6, AT2G24330, GLR2.2, RR12, PEX10, AGO5, AT2G28070, AT2G29880, WRKY25, AT2G30320, AT2G30330, RPT2, GSTF10, ASP1, AT2G31390, COP1, PKT3, AT2G33450, AT2G33730, AT2G34140, WAVE1, NF-YA4, WRKY35, VSR5, AT2G36460, DML1, MAT3, ABCB1, AT2G38010, AGT3, WRKY33, JAL23, AT2G39960, UBP5, PIP5K5, SFGH, PLDBETA1, AT2G42100, AT2G42360, NAC042, BIO2, AT2G43480, MAP1A, FLA8, ZAT, TLP3, GAPC1, SEC, SUVR4, AT3G05150, PRXIIF, CHR11, AT3G06450, GATA15, RPM1, GLR1.4, PK1, AT3G09470, DML2, HSP70, HAC5, MRP8, WBC27, CAX2, PPC3, EXPA12, IAA19, MTO3, CIPK1, CDC48C, HB-1
20706207	Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Mol. Syst. Biol. Jelle Van Leene , Jens Hollunder , Dominique Eeckhout , Geert Persiau , Eveline Van De Slijke , Hilde Stals , Gert Van Isterdael , Aurine Verkest , Sandy Neirynck , Yelle Buffel , Stefanie De Bodt , Steven Maere , Kris Laukens , Anne Pharazyn , Paulo C G Ferreira , Nubia Eloy , Charlotte Renne , Christian Meyer , Jean-Denis Faure , Jens Steinbrenner , Jim Beynon , John C Larkin , Yves Van de Peer , Pierre Hilson , Martin Kuiper , Lieven De Veylder , Harry Van Onckelen , Dirk InzÃ© , Erwin Witters , Geert De Jaeger	2010-08-10	-
19580813	A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase. J. Mol. Biol. Heinz Gut , Paola Dominici , Stefania Pilati , Alessandra Astegno , Maxim V Petoukhov , Dmitri I Svergun , Markus G GrÃ¼tter , Guido Capitani	2009-09-18	GAD, CAM1
17392553	High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes. Diabetes Care Raffaella Buzzetti , Sergio Di Pietro , Andrea Giaccari , Antonio Petrone , Mattia Locatelli , Concetta Suraci , Marco Capizzi , Maria Luisa Arpi , Elena Bazzigaluppi , Francesco Dotta , Emanuele Bosi , Non Insulin Requiring Autoimmune Diabetes Study Group	2007-04-01	GAD
16502469	The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses. Proteomics Jean-Emmanuel Sarry , Lauriane Kuhn , CÃ©line Ducruix , Alexandra Lafaye , Christophe Junot , VÃ©ronique Hugouvieux , AgnÃ¨s Jourdain , Olivier Bastien , Julie B Fievet , Dominique Vailhen , Badia Amekraz , Christophe Moulin , Eric Ezan , JÃ©rÃ´me Garin , Jacques Bourguignon	2006-04-01	AT2G01140, ACO3, NTRA, AT2G17630, NAP1;2, AT2G19940, AT2G20420, AT2G21250, FBA1, CCR2, RNR1, PAB4, CNGC6, AT2G24200, ARF3, PAG1, TUB7, UBA1, GSTF10, ASP1, PUR ALPHA-1, AT2G32240, AT2G33590, AT2G33800, AT2G35840, AT2G36460, LOS2, AT2G37760, AT2G39920, AT2G41380, SFGH, HSFB3, PLDBETA1, PP5.2, OASB, AT2G44060, ATCS, AT2G45030, AT2G45290, TRIP-1, UNE5, GAPC1, PRXIIF, AT3G08590, AT3G01860, GSTU8, AT3G09440, ADK1, CDC48, AT3G11830, HCHIB, HSP70, emb2742, PGK1, SERAT2;2, AT3G13235, NAP1;4, HSP60-3A, EIF4A1, AT3G14990, RABA1g, PLDALPHA1, TCTP, mtLPD2, GLN1.3, MS2, AT3G02530, AT3G18190, PREP1, AT3G20390, AT3G21950, PAC1, POP2, PKP-ALPHA, HSP60, ROF1, PP2AA2, G6PD5, AT3G29380, NIT2, NIT3, AT3G46170, PHS2, ALDH2B4, AT3G48990, MDAR1, AT3G52930, AT3G52990, AT3G53230, PPa4, AT3G53880, AT3G54470, TPI, ROC2, CCH, ADSS, AT3G58610, DL1E, AT3G60750
15604684	The root-specific glutamate decarboxylase (GAD1) is essential for sustaining GABA levels in Arabidopsis. Plant Mol. Biol. Nicolas BouchÃ© , Aaron Fait , Moriyah Zik , Hillel Fromm	2004-05-01	-

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