| Type | Description |
|---|---|
| Definition | transformation/transcription domain associated protein |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:29:00 | Our results uncover a role for TRRAP/KAT5 in promoting hepatocellular carcinoma cell proliferation by activating mitotic genes. Targeting the TRRAP/KAT5 complex is a potential therapeutic strategy for hepatocellular carcinoma | 31188495 |
| 2019-12-21 11:09:00 | Missense Variants in the TRRAP gene Causes Autism and Syndromic Intellectual Disability. | 30827496 |
| 2019-07-13 10:55:00 | TRRAP silencing attenuated p53 accumulation in lymphoma and colon cancer models, whereas TRRAP overexpression increased mutp53 levels, suggesting a role for TRRAP across cancer entities and p53 mutations. | 29653964 |
| 2019-05-18 12:12:00 | TRRAP, an essential component of multiple histone acetyltransferase complexes, was identified as a central regulator of multiciliated cell formation. | 29588376 |
| 2019-02-09 10:09:00 | TRRAP plays an important role in the regulation of the proliferation and stemness of ovarian cancer stem cells. | 29936929 |
| Type | IDs |
|---|---|
| Synonymous | PAF350/400, PAF400, STAF40, TR-AP, Tra1 |
| Gene |
UniProtKB-ID:
TRRAP_HUMAN
UniprotKB:
Q9Y4A5
UniParc:
UPI00004575B4,
UPI0000070329
EMBL:
AF110377,
AC004893,
CH236956,
AC004991,
AF076974,
CH471091
Ensembl:
ENSG00000196367
KO:
hsa:8295
|
| Nucleutide sequences |
EMBL-CDS:
AAD04629.1,
AAD09420.1,
AAC27675.2,
AAC62433.1,
EAL23887.1,
EAW76694.1
Ensembl_TRS:
ENST00000355540,
ENST00000359863
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347733,
ENSP00000352925
RefSeq:
NP_001362453.1,
NP_001231509.1,
NP_003487.1
|
| Others |
UniRef100:
UniRef100_Q9Y4A5
UniRef90:
UniRef90_Q9Y4A5
UniRef50:
UniRef50_Q9Y4A5
UniGene:
Hs.203952
CCDS:
CCDS59066.1,
CCDS5659.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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