| Type | Description |
|---|---|
| Definition | Restriction endonuclease, type II-like superfamily protein |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 11:12:00 | A. thaliana TOP3alpha conserved zinc-finger domain (ZFD) T1 is specifically required for targeting the topoisomerase activity to Holliday junction like recombination intermediates to enable their processing. In the case of an inactivated enzyme, this leads to cell death due to the masking of these intermediates, hindering their resolution by MUS81. | 30222730 |
| 2016-11-05 10:22:00 | SEND1 has at most a minor role in resolution of the Holliday junction but acts as an essential backup to MUS81 for resolution of toxic replication structures to ensure genome stability and to maintain telomere integrity. | 26704385 |
| 2016-09-24 10:18:00 | Data show that DNA polymerase zeta catalytic subunit REV3 cooperates with ATP-dependent DNA helicase RECQ4A and e ndonuclease MUS81 to repair DNA interstrand cross links. | 26474640 |
| 2011-04-16 14:21:00 | RECQ4A and MUS81 define RAD5A-independent pathways of DNA repair. RECQ4A and MUS81 act in parallel pathways presumably to resolve replication-associated DNA intermediates. | 20971895 |
| 2010-01-21 00:00:00 | AtMUS81 is involved in a secondary subset of meiotic crossovers that are interference insensitive. | 17696612 |
| Type | IDs |
|---|---|
| Synonymous | ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81, ATMUS81, F6I18.220, F6I18_220, MMS AND UV SENSITIVE 81 |
| Gene |
UniProtKB-ID:
MUS81_ARATH
UniprotKB:
Q5W9E7
UniParc:
UPI0000451CBA
EMBL:
CP002687,
AL161577,
AB177892,
AL022198,
EF154086
EnsemblGenome:
AT4G30870
KO:
ath:AT4G30870
|
| Nucleutide sequences |
EMBL-CDS:
BAD66696.1,
CAB79805.1,
CAA18206.1,
ABL98212.1,
AEE85822.1
Gene_ORFName:
F6I18.220
EnsemblGenome_TRS:
AT4G30870.1
|
| Protein sequencees |
EnsemblGenome_PRO:
AT4G30870.1
RefSeq:
NP_194816.2
|
| Others |
UniRef100:
UniRef100_Q5W9E7
UniRef90:
UniRef90_Q5W9E7
UniRef50:
UniRef50_Q5W9E7
UniGene:
At.51242
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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