| Type | Description |
|---|---|
| Definition | capping actin protein of muscle Z-line subunit alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 12:14:00 | in CAPZA1-overexpressing gastric epithelial cells infected with H. pylori, autolysosome formation is inhibited and CagA escapes autophagic degradation. | 30176157 |
| 2017-12-16 11:34:00 | Data show that CAPZA1 inhibits EMT in hepatocellular carcinoma (HCC cells by regulating actin cytoskeleton remodeling, thereby reducing the metastatic ability of the cells. | 28093067 |
| 2016-10-22 11:56:00 | Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ alpha-1) and profilin 2. | 26764407 |
| 2016-07-02 10:44:00 | mDia1 displaced from the barbed end by CapZ Actin Capping Protein can randomly slide along the actin filament and later return. | 26566078 |
| 2013-11-02 11:36:00 | The present study suggests that CAPZA1 could be a marker of good prognosis in gastric cancer and shows that CAPZA1 is associated with decreased cancer cell migration and invasion. | 23545944 |
| Type | IDs |
|---|---|
| Synonymous | CAPPA1, CAPZ, CAZ1 |
| Gene |
UniProtKB-ID:
CAZA1_HUMAN
UniprotKB:
P52907
UniParc:
UPI00001270FA
EMBL:
CR541819,
BT019364,
U56637,
CR407657,
BC000144,
AL603832,
AK223226,
AL929470
Ensembl:
ENSG00000116489
KO:
hsa:829
|
| Nucleutide sequences |
EMBL-CDS:
CAG28585.1,
AAC00533.1,
BAD96946.1,
AAH00144.1,
CAG46618.1,
AAV38171.1
Ensembl_TRS:
ENST00000263168
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263168
RefSeq:
XP_011540527.1,
NP_006126.1,
XP_016857913.1
|
| Others |
UniRef100:
UniRef100_P52907
UniRef90:
UniRef90_P52907
UniRef50:
UniRef50_P52907
UniGene:
Hs.744974
CCDS:
CCDS30805.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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