| Type | Description |
|---|---|
| Definition | eosinophil peroxidase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:52:00 | EPX is a useful biomarker for eosinophilic inflammation in chronic rhinosinusitis. | 30738839 |
| 2018-06-29 17:15:00 | Observational study of gene-disease association. (HuGE Navigator) | 19014520 |
| 2017-11-18 11:45:00 | peroxidase enzymes, like MPO and EPO, may play a fundamental role in inhibiting RANKL-induced osteoclast differentiation at inflammatory sites of bone fracture and injury. | 27836774 |
| 2017-07-22 11:14:00 | Both MPO and EPO are causatively involved in breast cancer progression and identified as potential therapeutic targets whereby specific novel inhibitors may reduce tumor growth and limit the occurrence of metastasis. | 28260049 |
| 2017-06-03 10:20:00 | The main significance of this work is the discovery of EPO as a novel ligand for the HER2 receptor. Following HER2 activation, EPO induces activation of FAK and subsequent activation of beta1-integrin, via inside-out signaling. This complex results in downstream activation of ERK1/2 and a sustained up regulation of both MUC4 and the HER2 receptor | 27519953 |
| Type | IDs |
|---|---|
| Synonymous | EPO, EPP, EPX-PEN, EPXD |
| Gene |
UniProtKB-ID:
PERE_HUMAN
UniprotKB:
P11678
UniParc:
UPI0000131629
EMBL:
M29909,
M29907,
M29906,
M29913,
DQ054598,
X14346,
M29910,
M29908,
M29904,
M29905,
M29911,
M29912
Ensembl:
ENSG00000121053
KO:
hsa:8288
|
| Nucleutide sequences |
EMBL-CDS:
AAY43126.1,
AAA58458.1,
CAA32530.1
Ensembl_TRS:
ENST00000225371
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000225371
RefSeq:
NP_000493.1
|
| Others |
UniRef100:
UniRef100_P11678
UniRef90:
UniRef90_P11678
UniRef50:
UniRef50_P11678
UniGene:
Hs.279259
CCDS:
CCDS11602.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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