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8277 TKTL1

8277

TKTL1

transketolase like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition transketolase like 1

研究结论

Date Results Publications
2020-11-21 13:29:00 Use of AKR1C1 and TKTL1 in the Diagnosis of Low-grade Squamous Intraepithelial Lesions from Mexican Women. 33109565
2020-09-19 16:31:00 Transketolase-Like Protein 1 and Glucose Transporter 1 in Gastric Cancer. 32434192
2020-06-13 11:52:00 For the first time we analyzed Apo10 and TKLT1 in patients with cholangiocellular (CCC), pancreatic (PC), and colorectal carcinoma (CRC). 31771043
2019-12-21 12:01:00 Homology modelling of TKTL1 and TKTL2 using transketolase (TKT) as template, revealed that both could assume a folded structure like TKT. TKTL1/2 presented a cleft of suitable dimensions between the homodimer surfaces that could accommodate the co-factor-substrate. An appropriate cavity and a hydrophobic nodule were also present in TKTL1/2 and implicated in aminopyrimidine and thiazole ring binding in TKT, respectively. 30646877
2018-12-22 10:28:00 The results obtained in this study suggest that pentose phosphate pathway and its key enzyme TKTL1 is altered throughout the prostate cancer tumorigenesis 30119993

名称对应

Type IDs
Synonymous TKR, TKT2
Gene
UniProtKB-ID: TKTL1_HUMAN, B7Z7I0_HUMAN
UniprotKB: P51854, B7Z7I0
UniParc: UPI0000211D08, UPI0001915092, UPI0000136FF4, UPI000014E356
EMBL: AK302044, Z49258, CH471172, BX664723, X91817, BC025382, U14622, AK292261, X91818
Ensembl: ENSG00000007350
KO: hsa:8277
Nucleutide sequences
EMBL-CDS: AAA21557.1, BAF84950.1, CAH69899.1, EAW72752.1, CAA62925.1, AAH25382.2, CAH69900.1, BAH13616.1
Ensembl_TRS: ENST00000369915, ENST00000369912
Protein sequencees
Ensembl_PRO: ENSP00000358931, ENSP00000358928
RefSeq: NP_001139406.1, NP_001139405.1, NP_036385.3
Others
UniRef100: UniRef100_B7Z7I0, UniRef100_P51854
UniRef90: UniRef90_P51854
UniRef50: UniRef50_P51854
UniGene: Hs.102866
CCDS: CCDS35448.1, CCDS55541.1

全选

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