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826714 RDR2

826714

RDR2

RNA-dependent RNA polymerase 2

protein-coding

Arabidopsis thaliana

基因描述

Type Description
Definition RNA-dependent RNA polymerase 2

研究结论

Date Results Publications
2020-01-18 11:09:00 RDR2 converts Pol IV transcripts into double-stranded RNAs and then typically adds an extra untemplated 3' terminal nucleotide to the second strands. The dicer endonuclease DCL3 cuts resulting duplexes to generate 24- and 23-nt siRNAs. 31398324
2016-08-27 12:44:00 The authors identified Pol IV and RDR2-dependent RNAs (P4R2 RNAs) that accumulate in dcl3 mutants and are diced into 24 nt RNAs by DCL3 in vitro. 26430765
2016-06-11 11:09:00 JMJ24 binds to RDR2 and is required for the basal level transcription of silenced loci in Arabidopsis. 26119694
2015-09-26 21:45:00 These findings begin to reveal features of Pol IV/RDR2-mediated transcription at the heart of genome stability in plants. 25414514
2013-02-23 11:19:00 Results suggest that the physical and mechanistic coupling of Pol IV and RDR2 results in the channeled synthesis of double-stranded precursors for siRNA biogenesis. 23142082

名称对应

Type IDs
Synonymous AtRDR2, RNA-dependent RNA polymerase 2, SILENCING MOVEMENT DEFICIENT 1, SMD1, T22B4.110, T22B4_110
Gene
UniProtKB-ID: RDR2_ARATH
UniprotKB: O82504
UniParc: UPI00000A8612
EMBL: AL049876, CP002687, AF080120, AL161531
EnsemblGenome: AT4G11130
KO: ath:AT4G11130
Nucleutide sequences
EMBL-CDS: AAC35535.1, CAB81214.1, AEE82976.1, CAB43048.1
Gene_ORFName: F2P3.11
EnsemblGenome_TRS: AT4G11130.1
Protein sequencees
EnsemblGenome_PRO: AT4G11130.1
RefSeq: NP_192851.1
Others
UniRef100: UniRef100_O82504
UniRef90: UniRef90_O82504
UniRef50: UniRef50_O82504
UniGene: At.43417

全选

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研究热度

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