| Type | Description |
|---|---|
| Definition | coagulation factor VIII associated 1 |
| Date | Results | Publications |
|---|---|---|
| 2013-07-06 12:05:00 | Orientations for FVIIIa are identified that bind to the membrane surface and support a new interaction between the A3 domain and the membrane, probably mediated in part by Arg(1719) and Arg(1721) | 23521092 |
| 2010-09-15 22:05:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| 2010-09-15 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-01-21 00:00:00 | The mutation Arg489Ala/Arg490Ala/Lys493Ala (489-3A) possessed near-normal affinity for FIXa and showed no effect on the Km for Factor X. | 15009463 |
| 2010-01-21 00:00:00 | cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant | 16513639 |
| Type | IDs |
|---|---|
| Synonymous | DXS522E, F8A, HAP40 |
| Gene |
UniProtKB-ID:
HAP40_HUMAN
UniprotKB:
P23610
UniParc:
UPI0000074369
EMBL:
BC071963,
M34677,
AY620000,
CH471172,
BX842559,
BC039693,
AY619999,
AY620001,
BX682237,
BX276110
Ensembl:
ENSG00000277150,
ENSG00000277203,
ENSG00000274791
KO:
hsa:474383,
hsa:8263,
hsa:474384
|
| Nucleutide sequences |
EMBL-CDS:
AAT44607.1,
AAH39693.1,
AAH71963.1,
EAW72648.1,
AAT44608.1,
AAT44606.1,
AAA35713.1
Ensembl_TRS:
ENST00000610495,
ENST00000622749,
ENST00000369505
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358518,
ENSP00000477530,
ENSP00000479624
RefSeq:
NP_036283.2
|
| Others |
UniRef100:
UniRef100_P23610
UniRef90:
UniRef90_P23610
UniRef50:
UniRef50_P23610
UniGene:
Hs.533543
CCDS:
CCDS35459.1,
CCDS35463.1,
CCDS35462.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员