| Type | Description |
|---|---|
| Definition | structural maintenance of chromosomes 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 13:03:00 | Significant phenotypical behavioral differences between individuals with de Lange syndrome caused by SMC1A variants and those caused by NIPBL variants. | 30295920 |
| 2020-05-16 12:39:00 | Holoprosencephaly is associate with variants in the two X-linked cohesin complex genes, SMC1A and STAG2. | 31334757 |
| 2020-03-28 10:44:00 | NEAT1 repressed the expression of miR-23a-3p, and therefore promoted SMC1A, which in turn suppressed myeloid leukemia cell proliferation and enhanced apoptosis | 30246348 |
| 2019-12-07 11:41:00 | Knockdown of CRL7(SMU1) components or loss of H2B ubiquitylation leads to defective sister chromatid cohesion, which is rescued by restoration of SMC1a expression. | 29507117 |
| 2019-08-17 10:05:00 | observations suggest that phosphorylation of SMC1A is a vital event in tumorigenesis and disease progression in hepatocellular carcinoma thus necessitating further investigation. | 29988990 |
| Type | IDs |
|---|---|
| Synonymous | CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB |
| Gene |
UniProtKB-ID:
SMC1A_HUMAN,
Q68EN4_HUMAN,
A0A384MR33_HUMAN,
G8JLG1_HUMAN
UniprotKB:
Q14683,
Q68EN4,
A0A384MR33,
G8JLG1
UniParc:
UPI0003833506,
UPI0000135A4D,
UPI000041A249
EMBL:
GQ900894,
AC233728,
BC112127,
S78271,
AL161779,
D80000,
CH471154,
BC080185,
Z97054
Ensembl:
ENSG00000072501
KO:
hsa:8243
|
| Nucleutide sequences |
EMBL-CDS:
BAA11495.2,
CAI42646.1,
AAB34405.1,
CAI42089.1,
AAI12128.1,
AAH80185.1,
EAW93150.1,
ADO22411.1
Gene_ORFName:
hCG_18494
Ensembl_TRS:
ENST00000322213,
ENST00000375340,
ENST00000675504
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000323421,
ENSP00000364489,
ENSP00000502524
RefSeq:
NP_006297.2,
NP_001268392.1
|
| Others |
UniRef100:
UniRef100_Q14683,
UniRef100_Q68EN4,
UniRef100_G8JLG1
UniRef90:
UniRef90_Q14683,
UniRef90_Q68EN4
UniRef50:
UniRef50_Q68EN4,
UniRef50_Q14683
UniGene:
Hs.211602
CCDS:
CCDS14352.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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