| Type | Description |
|---|---|
| Definition | calpain 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | Calpain-2 participates in the process of calpain-1 inactivation. | 33078830 |
| 2020-05-16 11:27:00 | Heat stress reduces calpain-2 expression, which then activates p38, leading to cardiomyocyte apoptosis and heart dysfunction. | 30417356 |
| 2020-02-01 13:31:00 | protein levels of CAPN2 are regulated by miR-223, acting directly on the 3'-untranslated region as well as by miR-145, which acts via an increase in HDAC2 | 31634637 |
| 2019-10-26 11:14:00 | Isoform-specific hyperactivation of calpain-2, but not calpain-1 occurs at the synapse early in the pathogenesis of Alzheimer's disease potentially contributing to the deregulation of synaptic signaling in humans and mice models. | 30177812 |
| 2019-09-07 10:13:00 | The mechanisms that drove both mechanosensitive cell adhesion and motility converged on calpain 2, an intracellular protease important for talin cleavage and focal adhesion turnover. | 29909039 |
| Type | IDs |
|---|---|
| Synonymous | CANP2, CANPL2, CANPml, mCANP |
| Gene |
UniProtKB-ID:
CAN2_HUMAN,
B4DN77_HUMAN,
Q59EF6_HUMAN
UniprotKB:
P17655,
B4DN77,
Q59EF6
UniParc:
UPI00017A772F,
UPI000059D0B9,
UPI00004F6E6C,
UPI00019154C4
EMBL:
BC007686,
BC021303,
AK316211,
BC011828,
AK297800,
AC096542,
AF261089,
J04700,
AC099065,
M23254,
AB209855,
AY835586
Ensembl:
ENSG00000162909
KO:
hsa:824
|
| Nucleutide sequences |
EMBL-CDS:
AAV80421.1,
BAH14582.1,
AAH07686.1,
AAH11828.1,
AAA35645.1,
AAF99682.1,
AAH21303.1,
AAA52760.1,
BAG60139.1,
BAD93092.1
Ensembl_TRS:
ENST00000433674,
ENST00000295006
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000413158,
ENSP00000295006
RefSeq:
NP_001139540.1,
NP_001739.3
|
| Others |
UniRef100:
UniRef100_B4DN77,
UniRef100_Q59EF6,
UniRef100_P17655
UniRef90:
UniRef90_H0X767,
UniRef90_P17655
UniRef50:
UniRef50_P17655,
UniRef50_H0X767
UniGene:
Hs.350899
CCDS:
CCDS53478.1,
CCDS31035.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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