| Type | Description |
|---|---|
| Definition | zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:31:00 | ZRSR2 mutation in a child with refractory macrocytic anemia and Down Syndrome. | 31361176 |
| 2019-06-15 10:56:00 | This meta-analysis indicates a positive effect of SF3B1 and an adverse prognostic effect of SRSF2, U2AF1, and ZRSR2 mutations in patients with myelodysplastic syndrome. | 31124956 |
| 2017-10-21 11:15:00 | We conclude that the common clinical features of patients with an isolated mutation of ZRSR2 are a macrocytic anemia without leukopenia, thrombocytopenia or an increase in marrow blast percentage | 28942350 |
| 2016-02-13 11:48:00 | ZRSR2 has a role in RNA splicing; dysregulated splicing of U12-type introns is a characteristic feature of ZRSR2 mutations in myelodysplastic syndrome | 25586593 |
| 2015-08-08 11:14:00 | The mutational status of the SRSF2, U2AF1 and ZRSR2 did not affect the response rate or survival in MDS patients who had received first-line decitabine treatment. | 25964599 |
| Type | IDs |
|---|---|
| Synonymous | U2AF1-RS2, U2AF1L2, U2AF1RS2, URP, ZC3H22 |
| Gene |
UniProtKB-ID:
U2AFM_HUMAN
UniprotKB:
Q15696
UniParc:
UPI0000137929
EMBL:
BC113454,
AC004106,
AC096510,
BC113480,
D49677
Ensembl:
ENSG00000169249
KO:
hsa:8233
|
| Nucleutide sequences |
EMBL-CDS:
AAI13481.1,
BAA08533.1,
AAI13455.1
Ensembl_TRS:
ENST00000307771
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000303015
RefSeq:
XP_011543891.2,
XP_024308223.1,
XP_016885370.1,
XP_005274654.2,
NP_005080.1,
XP_016885372.1,
XP_024308224.1,
XP_016885371.1
|
| Others |
UniRef100:
UniRef100_Q15696
UniRef90:
UniRef90_Q15696
UniRef50:
UniRef50_Q15696
UniGene:
Hs.171909
CCDS:
CCDS14172.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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