| Type | Description |
|---|---|
| Definition | patatin like phospholipase domain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-03 10:51:00 | These results strongly suggest that PNPLA9, -6 and -4 play a key role in GPL turnover and homeostasis in human cells. A hypothetical model suggesting how these enzymes could recognize the relative concentration of the different GPLs is proposed | 27317427 |
| 2010-01-21 00:00:00 | iPLA2epsilon (adiponutrin), iPLA2zeta (TTS-2.2), and iPLA2eta (GS2) are three novel TAG lipases/acylglycerol transacylases that likely participate in TAG hydrolysis and the acyl-CoA independent transacylation of acylglycerols | 15364929 |
| 2010-01-21 00:00:00 | we report the identity of an inhibitor, TIP47, which prevents retinylester hydrolysis catalyzed by GS2 lipase and hormone-sensitive lipase | 16741517 |
| 2010-01-21 00:00:00 | GS2 promotes RE accumulation and may do so either as a catalyst or as a regulatory protein that enhances retinylesters formation catalyzed by other acyl transferases. | 19181555 |
| 2010-01-21 00:00:00 | The GS2 gene (PNPLA4) encodes a keratinocyte retinyl ester hydrolase. The protein also catalyzes fatty acyl CoA-dependent and -independent retinol esterification, using triolein as substrate and generates diacylglyceride and free fatty acid. | 15955102 |
| Type | IDs |
|---|---|
| Synonymous | DXS1283E, GS2, iPLA2eta |
| Gene |
UniProtKB-ID:
PLPL4_HUMAN,
A0A024RBU8_HUMAN
UniprotKB:
P41247,
A0A024RBU8
UniParc:
UPI000012BB6D,
UPI0000418A17
EMBL:
AC005296,
U08890,
U08891,
BC020746,
AK304586,
U08888,
CH471074,
U08893,
AK289888,
U03886,
U08889,
U08892
Ensembl:
ENSG00000006757
KO:
hsa:8228
|
| Nucleutide sequences |
EMBL-CDS:
AAA16491.1,
EAW98752.1,
AAH20746.1,
BAG65374.1,
BAF82577.1,
AAA17838.1,
EAW98753.1
Gene_ORFName:
hCG_1981647
Ensembl_TRS:
ENST00000444736,
ENST00000537427,
ENST00000381042
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000415245,
ENSP00000443157,
ENSP00000370430
RefSeq:
NP_004641.1,
XP_011543890.1,
NP_001166143.1,
NP_001135861.1
|
| Others |
UniRef100:
UniRef100_P41247
UniRef90:
UniRef90_P41247
UniRef50:
UniRef50_P41247
UniGene:
Hs.264
CCDS:
CCDS55368.1,
CCDS14129.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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