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8224 SYN3

8224

SYN3

synapsin III

protein-coding

Homo sapiens

基因描述

Type Description
Definition synapsin III

研究结论

Date Results Publications
2019-06-01 11:34:00 Synapsin III is a crucial alpha-synuclein interactant and a key component of Lewy bodies fibrils in the brain of patients affected by Parkinson's disease. 29330884
2017-06-10 11:11:00 These findings contribute to previous work showing dysregulation of Synapsins, particularly SYN2, in mood disorders and improve our understanding of the regulatory mechanisms that precipitate these changes likely leading to the BD or MDD phenotype. 27515700
2016-07-16 10:08:00 Syn-3 may mimic Syn-1A in the ability to bind and modulate Cavs, but preferring Cav2.3 to perhaps participate in triggering fusion of newcomer insulin SGs during second-phase GSIS. 26848587
2016-04-02 10:57:00 These findings support a reciprocal modulatory interaction of alpha-syn and synapsin III in the regulation of dopamine neuron synaptic function. 25967550
2015-01-10 13:23:00 The variations of MnSOD (rs4880) and SYN III (rs3788470, rs3827336, rs5998557) were not major risk factors for PD among Chinese, at least in our study populations 24586301

名称对应

Type IDs
Gene
UniProtKB-ID: SYN3_HUMAN, Q59EX7_HUMAN, Q17R54_HUMAN, A0A024R1I8_HUMAN
UniprotKB: O14994, Q59EX7, Q17R54, A0A024R1I8
UniParc: UPI00001365D3, UPI0000DA5900, UPI00004F6DC6
EMBL: BC075066, BC117460, Z80902, Z98256, BC075065, AF046873, Z82246, Z71183, CH471095, CR456589, Z83846, AB209684, Z82181, BC143874
Ensembl: ENSG00000185666
KO: hsa:8224
Nucleutide sequences
EMBL-CDS: AAI43875.1, CAG30475.1, EAW60034.1, AAH75066.1, AAC15101.1, AAH75065.1, BAD92921.1, AAI17461.1, EAW60035.1
Gene_ORFName: hCG_1811993
Ensembl_TRS: ENST00000358763
Protein sequencees
Ensembl_PRO: ENSP00000351614
RefSeq: XP_016884454.1, NP_001129246.1, NP_001356837.1, XP_016884450.1, NP_001356836.1, XP_016884452.1, XP_016884451.1, NP_001356839.1, NP_003481.3, NP_598344.2, XP_011528712.1, NP_001356838.1, XP_011528707.1
Others
UniRef100: UniRef100_Q17R54, UniRef100_O14994
UniRef90: UniRef90_O14994, UniRef90_Q17R54
UniRef50: UniRef50_O70441
UniGene: Hs.608750
CCDS: CCDS13908.1

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