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821600 POLGAMMA1

821600

POLGAMMA1

polymerase gamma 1

protein-coding

Arabidopsis thaliana

基因描述

Type Description
Definition polymerase gamma 1

研究结论

Date Results Publications
2019-07-13 11:09:00 The interaction of Twinkle with Pol1A or Pol1B mimics the minimal DNA replisomes of T7 phage and those present in mammalian mitochondria. However, while T7 and mammals absolutely require their homolog of Twinkle DNA helicase-primase, Arabidopsis Twinkle mutants are seemingly unaffected by this loss. 31170927
2018-10-06 12:15:00 PolIA & PolIB are functionally equipped to play a role in short-patch BER and suggest a major role of PolIA & PolIB in a predicted long-patch base excision repair (BER) sub-pathway. We propose that the acquisition of insertion 1 in the polymerization domain of PolIA & PolIB was a key component in their evolution as BER associated and replicative DNA polymerases. 29522990
2017-11-11 13:09:00 both AtPolIA and AtPolIB are efficient translesion DNA synthesis polymerases, providing the first example of a family-A DNAP with an active exonuclease domain that efficiently bypasses an AP site. 28977655
2014-04-05 10:58:00 results suggest that polIB (At3G29540) mutants undergo an adjustment in cell homeostasis, enabling them to maintain functional mitochondria at the cost of normal cell expansion and plant growth 23167278
2011-06-18 11:32:00 UV-B irradiation enhances expression of AtPollambda in wild-type Arabidopsis. Overexpression partially complements DNA damage repair efficiency of atpollambda mutants. 21227935

名称对应

Type IDs
Synonymous PolIB, polymerase I B, polymerase gamma 1
Gene
UniProtKB-ID: POLIB_ARATH, F4JEQ3_ARATH
UniprotKB: Q84ND9, F4JEQ3
UniParc: UPI0000191FC6, UPI0001E92DEF
EMBL: AB211533, CP002686, AY195962, AP000410, AK226811
EnsemblGenome: AT3G20540
KO: ath:AT3G20540
Nucleutide sequences
EMBL-CDS: AEE76392.1, BAB01162.1, AAO34128.1, BAE10874.1, BAE98907.1, AEE76393.1
Gene_ORFName: K10D20.8
EnsemblGenome_TRS: AT3G20540.1
Protein sequencees
EnsemblGenome_PRO: AT3G20540.1
RefSeq: NP_188690.3, NP_001189942.1
Others
UniRef100: UniRef100_Q84ND9, UniRef100_F4JEQ3
UniRef90: UniRef90_Q84ND9
UniRef50: UniRef50_F4I6M1
UniGene: At.38221, At.64528

全选

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