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81905 Cacng8

81905

Cacng8

calcium channel, voltage-dependent, gamma subunit 8

protein-coding

Mus musculus

基因描述

Type Description
Definition calcium channel, voltage-dependent, gamma subunit 8

研究结论

Date Results Publications
2018-10-13 10:50:00 AMPA receptor auxiliary subunit gamma-8, via its PDZ-binding motif, is indispensable for both basal synaptic transmission and Long-term potentiation. 29581259
2018-06-09 12:11:00 Critically, by altering the two interacting loops of gamma2 and Tduanyu37 gamma8, the authors could entirely remove all allosteric modulation of GluA2, without affecting formation of AMPA complexes. 28871958
2017-10-07 10:11:00 these findings demonstrate that is a crucial mediator of CaMKII-dependent Long Term Potentiation and therefore a molecular target that controls synaptic plasticity and associated cognitive functions. 27667007
2016-09-10 10:27:00 gamma-8 is the only Tduanyu37 expressed at nonperforated type of pyramidal cell synapses, playing an essential role in low-density or basal AMPAR expression 27076426
2016-02-20 11:55:00 This study demonstrated that genetic inactivation of this specific population of AMPA receptors results in modest changes in behavior characterized by a mild hyperactivity. 25921737

名称对应

Type IDs
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_573453.2
Others
UniGene: Mm.357990

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

University of California

7
2

Yale University School of Medicine

2
3

Brain Research Institute

2
4

Institute of Developmental Genetics

2
5

RIKEN Yokohama Institute 1-7-22 Suehiro-cho

1
热点人员
排名 研究人员 文献
1

Roger A Nicoll

7
2

David S Bredt

5
3

Susumu Tomita

5
4

Akihiko S Kato

3
5

He Wang

2
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