| Type | Description |
|---|---|
| Definition | symplekin |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 12:00:00 | The significance of nuclear symplekin in tumorigenesis is also highlighted, and ERK-dependent phosphorylation represents a mechanism for its subcellular sorting. | 28630428 |
| 2018-12-01 11:28:00 | Results indicated that reductase becomes destabilized in the absence of UBIAD1, resulting in reduced cholesterol synthesis and intracellular accumulation. Findings further establish UBIAD1 as a central player in the reductase ERAD pathway and regulation of isoprenoid synthesis. | 29167270 |
| 2018-11-10 11:25:00 | Research proved that high Rab11 expression enhances cellular multiplication and invasiveness of bladder cancer, possibly by regulating the NF-kappaB signaling pathway. | 30032159 |
| 2017-09-23 11:49:00 | Data indicate rs56848936 in the gene symplekin protein (SYMPK) at 19q13.3, associated with colon cancer risk. | 28295283 |
| 2015-08-22 11:29:00 | CPSF2 and SYMPK, are RBFOX2 cofactors for both inclusion and exclusion of internal exons. | 25921069 |
| Type | IDs |
|---|---|
| Synonymous | SPK, SYM |
| Gene |
UniProtKB-ID:
SYMPK_HUMAN,
A0A024R0R6_HUMAN
UniprotKB:
Q92797,
A0A024R0R6
UniParc:
UPI00027DB7A6,
UPI00002026C0
EMBL:
DB328640,
BC006567,
BC006536,
Y10931,
U49240,
CH471126,
U88726,
BC030214,
AB209024
Ensembl:
ENSG00000125755
KO:
hsa:8189
|
| Nucleutide sequences |
EMBL-CDS:
BAD92261.1,
CAA71861.1,
AAH06536.2,
AAH06567.2,
AAH30214.1,
AAB58578.1,
AAC50667.1,
EAW57391.1,
EAW57389.1
Gene_ORFName:
hCG_20812
Ensembl_TRS:
ENST00000245934
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000245934
RefSeq:
XP_005259343.1,
NP_004810.2,
XP_011525656.1
|
| Others |
UniRef100:
UniRef100_Q92797
UniRef90:
UniRef90_Q92797
UniRef50:
UniRef50_Q92797
UniGene:
Hs.515475
CCDS:
CCDS12676.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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