| Type | Description |
|---|---|
| Definition | fumarylacetoacetate hydrolase domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:41:00 | Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse. | 32068790 |
| 2019-06-08 11:46:00 | Data indicate that FAH domain-containing protein 1 (FAHD1) is a mitochondrial protein displaying both acylpyruvate hydrolase (ApH) and oxaloacetate decarboxylase (ODx) activity. | 30348641 |
| 2019-04-27 12:15:00 | genetic inactivation of FAHD1 in human cells induces a specific form of cellular senescence. | 30055189 |
| 2017-10-07 12:36:00 | The results indicate that FAHD1 is required for mitochondrial function in human cells and provide additional support to the growing evidence that mitochondrial dysfunction can induce cellular senescence by metabolic alterations independent of the DNA damage response pathway. | 28286170 |
| 2016-05-14 11:49:00 | we recently identified human FAH domain containing protein-1 (FAHD1) as the first eukaryotic oxaloacetate decarboxylase..these data establish a role of fahd-1 to maintain mitochondrial function and consequently physical activity | 26266933 |
| Type | IDs |
|---|---|
| Synonymous | C16orf36, YISKL |
| Gene |
UniProtKB-ID:
FAHD1_HUMAN
UniprotKB:
Q6P587
UniParc:
UPI00002262FC,
UPI0000037BCE,
UPI000051946E
EMBL:
BC063017,
AL136720,
AC012180,
CR533499,
AE006639,
AL031722,
AK094199
Ensembl:
ENSG00000180185
KO:
hsa:81889
|
| Nucleutide sequences |
EMBL-CDS:
AAH63017.1,
BAC04308.1,
CAG38530.1,
CAB66654.1,
AAK61295.1
Ensembl_TRS:
ENST00000615972,
ENST00000382668,
ENST00000427358,
ENST00000382666
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482534,
ENSP00000372114,
ENSP00000398053,
ENSP00000372112
RefSeq:
NP_112485.1,
NP_001018114.1,
NP_001135870.1
|
| Others |
UniRef100:
UniRef100_Q6P587
UniRef90:
UniRef90_Q6P587
UniRef50:
UniRef50_Q6P587
UniGene:
Hs.513265
CCDS:
CCDS32367.1,
CCDS45380.1,
CCDS10448.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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