| Type | Description |
|---|---|
| Definition | LAS1 like, ribosome biogenesis factor |
| Date | Results | Publications |
|---|---|---|
| 2020-02-28 17:20:00 | Recruitment of the protein complex 5FMC to Zbp-89, a zinc-finger transcription factor, affects its sumoylation status and transactivation potential.[5FMC] | 22872859 |
| 2012-07-28 10:41:00 | LAS1L interacts with PELP1, TEX10, and WDR18, the mammalian homologues of the budding yeast Rix1 complex, along with NOL9 and SENP3, to form a novel nucleolar complex that cofractionates with the 60S preribosomal subunit. | 22190735 |
| 2012-02-25 10:06:00 | Analysis of high-molecular-weight RNAs confirmed that Las1L is required for ITS2 processing,which separates the 5.8S and 25S/28S rRNAs, as 32S was found to accumulate and 12S to diminish upon Las1L depletion. | 22083961 |
| 2010-10-23 10:43:00 | Data demonstrate that Las1L is essential for cell proliferation and biogenesis of the 60S ribosomal subunit. | 20647540 |
| Type | IDs |
|---|---|
| Synonymous | Las1-like, WTS, dJ475B7.2 |
| Gene |
UniProtKB-ID:
LAS1L_HUMAN
UniprotKB:
Q9Y4W2
UniParc:
UPI000013C4DC,
UPI0000073CB7,
UPI000006E30F,
UPI0000371DC8
EMBL:
BC019302,
AF116730,
AK074087,
AK022587,
BC018610,
DQ323624,
AL050306,
BC014545
Ensembl:
ENSG00000001497
KO:
hsa:81887
|
| Nucleutide sequences |
EMBL-CDS:
BAB84913.1,
AAH19302.1,
BAB14114.1,
AAH14545.1,
AAH18610.1,
AAO15306.1,
ABD39127.1
Gene_ORFName:
MSTP060
Ensembl_TRS:
ENST00000374804,
ENST00000374807,
ENST00000484069,
ENST00000374811
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363937,
ENSP00000473471,
ENSP00000363944,
ENSP00000363940
RefSeq:
NP_001362258.1,
XP_016885368.1,
XP_011529347.1,
XP_005262363.1,
NP_001362263.1,
NP_001362266.1,
NP_112483.1,
NP_001362265.1,
NP_001164121.1,
XP_011529348.1,
NP_001362264.1,
NP_001362257.1,
NP_001362260.1,
NP_001164120.1,
NP_001362261.1,
NP_001362262.1,
NP_001362259.1
|
| Others |
UniRef100:
UniRef100_Q9Y4W2
UniRef90:
UniRef90_Q9Y4W2
UniRef50:
UniRef50_Q9Y4W2
UniGene:
Hs.522675
CCDS:
CCDS14381.1,
CCDS55434.1,
CCDS55433.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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