| Type | Description |
|---|---|
| Definition | sprouty RTK signaling antagonist 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:15:00 | A Sprouty4 Mutation Identified in Kallmann Syndrome Increases the Inhibitory Potency of the Protein towards FGF and Connected Processes. | 33670044 |
| 2020-09-12 16:04:00 | SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells. | 31645544 |
| 2020-06-27 11:26:00 | The transient downregulation of the SPRY4 expression via small interfering RNA (siRNA) showed significant enhancement of the osteogenic differentiation of adipose-derived stem cells. | 30982407 |
| 2020-05-16 11:54:00 | The authors demonstrated that Spry4 functions as tumor-suppressing protein in cancerogenesis of brain malignancies. | 31374860 |
| 2020-05-02 12:04:00 | High expression of SPRY4 was an independent biomarker of favorable prognosis in PHCC | 31761616 |
| Type | IDs |
|---|---|
| Synonymous | HH17 |
| Gene |
UniProtKB-ID:
SPY4_HUMAN,
A0A0C4DFS6_HUMAN
UniprotKB:
Q9C004,
A0A0C4DFS6
UniParc:
UPI000002B427,
UPI00000015D0,
UPI0000167871
EMBL:
BC125096,
AF227517,
AY538661,
AK096464,
BC125095,
AF227516,
AC091825
Ensembl:
ENSG00000187678
KO:
hsa:81848
|
| Nucleutide sequences |
EMBL-CDS:
AAI25096.1,
AAK00652.1,
AAS46253.1,
AAK00653.1,
AAI25097.1,
BAC04798.1
Ensembl_TRS:
ENST00000434127,
ENST00000344120
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399468,
ENSP00000344967
RefSeq:
XP_011535987.1,
NP_001120968.1,
NP_001280219.1,
XP_016865399.1,
NP_112226.2,
NP_001280218.1
|
| Others |
UniRef100:
UniRef100_Q9C004
UniRef90:
UniRef90_Q9C004
UniRef50:
UniRef50_Q9C004
UniGene:
Hs.323308
CCDS:
CCDS47296.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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