| Type | Description |
|---|---|
| Definition | ADAM metallopeptidase with thrombospondin type 1 motif 10 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 12:21:00 | Using siRNA, over-expression and mutagenesis, it was found ADAMTS6 inhibits and ADAMTS10 is required for focal adhesions, epithelial cell-cell junction formation, and microfibril deposition. | 27779234 |
| 2013-05-11 11:05:00 | These findings support the Gly661Arg mutation of ADAMTS10 as the likely cause of POAG in beagles. | 23422823 |
| 2011-07-16 10:36:00 | ADAMTS10 participates in microfibril biogenesis rather than in fibrillin-1 turnover | 21402694 |
| 2010-01-21 00:00:00 | Mutations in ADAMTS10 gene is not responsible for microspherophakia. | 19696795 |
| 2010-01-21 00:00:00 | infer that folding of the complex C-terminal ancillary domain is the rate-limiting step in biosynthesis of ADAMTS10, and that it (but not catalytic domain) is sensitive to subtle changes in efficiency of signal peptide cleavage. | 18567016 |
| Type | IDs |
|---|---|
| Synonymous | ADAM-TS10, ADAMTS-10, WMS, WMS1 |
| Gene |
UniProtKB-ID:
ATS10_HUMAN,
A0A0A0MQW6_HUMAN,
Q59FE5_HUMAN,
Q6ZN14_HUMAN
UniprotKB:
Q9H324,
A0A0A0MQW6,
Q59FE5,
Q6ZN14
UniParc:
UPI000035E7C0,
UPI00025D3090,
UPI0001AE642B,
UPI00004F6D1E,
UPI000013D883
EMBL:
AK131414,
AC243312,
AB209515,
AC130469,
AC092315,
AF163762
Ensembl:
ENSG00000142303
KO:
hsa:81794
|
| Nucleutide sequences |
EMBL-CDS:
AAG35563.1,
BAD92752.1,
BAD18561.1
Ensembl_TRS:
ENST00000595838,
ENST00000270328,
ENST00000597188
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000470501,
ENSP00000270328,
ENSP00000471851
RefSeq:
XP_006722980.1,
NP_001269281.1,
XP_016882827.1,
XP_016882829.1,
XP_016882828.1,
NP_112219.3
|
| Others |
UniRef100:
UniRef100_Q6ZN14,
UniRef100_Q9H324,
UniRef100_A0A0A0MQW6,
UniRef100_Q59FE5
UniRef90:
UniRef90_Q59FE5,
UniRef90_Q9H324,
UniRef90_Q9H324-2
UniRef50:
UniRef50_A0A3P4KAK7,
UniRef50_Q9H324,
UniRef50_Q9H324-2
UniGene:
Hs.657508
CCDS:
CCDS12206.1,
CCDS62529.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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