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81788 NUAK2

81788

NUAK2

NUAK family kinase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition NUAK family kinase 2

研究结论

Date Results Publications
2021-03-13 13:17:00 A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling. 32845958
2020-11-28 13:15:00 NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP. 32001115
2018-05-26 10:48:00 Data (including data from studies in knockout and transgenic mice) suggest that NUAK2/SNARK is involved in both adipose inflammation and energy metabolism in adipocytes; additionally, genome-wide association studies suggest that 2 SNPs in NUAK2/SNARK (rs4682880, rs4682676) are associated with obesity in women. 29298809
2017-03-04 12:06:00 miR143 inhibited the proliferation, migration and invasion of the glioblastoma cells by degrading NUAK2 in glioblastoma. 27081712
2016-10-29 12:03:00 Sucrose non-fermenting AMPK related kinase/Pentraxin 3 combined role in immunometabolic signaling and DNA damage response is proposed to accelerate cardiovascular complications in systemic lupus erythematosus patients 25732129

名称对应

Type IDs
Synonymous SNARK
Gene
UniProtKB-ID: NUAK2_HUMAN, B4E0Y5_HUMAN
UniprotKB: Q9H093, B4E0Y5
UniParc: UPI00017A84A8, UPI0000037D77
EMBL: AK074830, AL136891, AK303577, BC017306
Ensembl: ENSG00000163545
KO: hsa:81788
Nucleutide sequences
EMBL-CDS: BAC11234.1, CAB66825.1, AAH17306.1, BAG64597.1
Ensembl_TRS: ENST00000367157
Protein sequencees
Ensembl_PRO: ENSP00000356125
RefSeq: XP_005245572.1, NP_112214.3
Others
UniRef100: UniRef100_Q9H093
UniRef90: UniRef90_Q9H093
UniRef50: UniRef50_Q9H093
UniGene: Hs.497512
CCDS: CCDS1453.2

全选

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研究热度

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