| Type | Description |
|---|---|
| Definition | elongation factor for RNA polymerase II |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 14:43:00 | E1A-associated p300 protein -mediated site-specific acetylation increases, whereas histone deacetylase 3-mediated deacetylation decreases, transcriptional elongation factor ELL stability through polyubiquitylation by the E3 ubiquitin ligase Siah1. Knockdown of human cell cycle and apoptosis regulator 2 reduces ELL levels and expression of a significant number of genes, including those involved in glucose metabolism. | 32152128 |
| 2017-11-04 13:12:00 | The results indicate that p53 interferes with the interaction between ELL/EAF and ICE1 and represses transcription of small nuclear RNA genes by Pol II. | 27268141 |
| 2016-09-03 12:13:00 | This work reveals a previously unrecognized function for ELL as an E3 ubiquitin ligase for c-Myc and a potential tumour suppressor. | 27009366 |
| 2015-11-28 10:33:00 | The Tax oncogene enhances ELL incorporation into p300 and P-TEFb containing protein complexes to activate transcription. | 26188510 |
| 2014-03-22 11:40:00 | eleven-nineteen lysine-rich leukemia protein enhanced E2F1 deacetylation via recruitment of histone deacetylase 1 | 24344198 |
| Type | IDs |
|---|---|
| Synonymous | C19orf17, ELL1, MEN, PPP1R68 |
| Gene |
UniProtKB-ID:
ELL_HUMAN,
U3KQ90_HUMAN
UniprotKB:
P55199,
U3KQ90
UniParc:
UPI0000062324,
UPI000059D6B7
EMBL:
AC010335,
U16282,
BC049195
Ensembl:
ENSG00000105656
KO:
hsa:8178
|
| Nucleutide sequences |
EMBL-CDS:
AAH49195.1,
AAA57120.1
Ensembl_TRS:
ENST00000262809,
ENST00000596124
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262809,
ENSP00000475648
RefSeq:
NP_006523.1,
XP_016882826.1,
XP_016882824.1,
XP_016882825.1,
XP_011526632.2
|
| Others |
UniRef100:
UniRef100_P55199
UniRef90:
UniRef90_P55199
UniRef50:
UniRef50_P55199
UniGene:
Hs.515260
CCDS:
CCDS12380.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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