Sctr - secretin receptor-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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81779 Sctr

基因描述

Type	Description
Definition	secretin receptor

研究结论

Date	Results	Publications
2017-05-06 11:00:00	Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.	27330080
2012-12-22 11:42:00	Secretin receptors are overexpressed in various endocrine tumor cells and play a proproliferative role in pheochromocytoma and adrenocortical carcinoma cells.	22692904
2011-09-10 12:10:00	Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.	21566140
2011-08-06 10:37:00	Data show that in secretin/secretin receptor binding, the alpha-helix in natural secretin was oriented approximately parallel to the amino-terminal alpha-helix of the receptor.	21388146
2010-01-21 00:00:00	refined model of the intact receptor was also fully consistent with the spatial approximation of the Trp(48)-Asp(49)-Asn(50) endogenous agonist segment with the third extracellular loop region that it has been shown to photolabel	17827151

名称对应

Type	IDs
Gene	UniProtKB-ID: SCTR_RAT UniprotKB: P23811 UniParc: UPI000013569A EMBL: X59132, BC081781 KO: rno:81779
Nucleutide sequences	EMBL-CDS: CAA41849.1, AAH81781.1
Protein sequencees	RefSeq: NP_112377.1
Others	UniRef100: UniRef100_P23811 UniRef90: UniRef90_P23811 UniRef50: UniRef50_Q5FWI2 UniGene: Rn.32256

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
30449620	Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation. Cell Yongguo Li , Katharina Schnabl , Sarah-Madeleine Gabler , Monja WillershÃ¤user , Josefine Reber , Angelos Karlas , Sanna Laurila , Minna Lahesmaa , Mueez U Din , Andrea Bast-Habersbrunner , Kirsi A Virtanen , Tobias Fromme , Florian Bolze , Libbey S O'Farrell , Jorge Alsina-Fernandez , Tamer Coskun , Vasilis Ntziachristos , Pirjo Nuutila , Martin Klingenspor	2018-11-29	-
27330080	Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors. J Biol Chem Kaleeckal G Harikumar , Mary Lou Augustine , Leo T O Lee , Billy K C Chow , Laurence J Miller	2016-08-12	-
24273196	Lipolytic actions of secretin in mouse adipocytes. J Lipid Res Revathi Sekar , Billy K C Chow	2014-02-01	-
23264731	MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. J Cell Sci Ka-wing Fong , Justin Wai-chung Leung , Yujing Li , Wenqi Wang , Lin Feng , Wenbin Ma , Dan Liu , Zhou Songyang , Junjie Chen	2013-02-01	-
22692904	Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Mol. Endocrinol. Misu Lee , Beatrice Waser , Jean-Claude Reubi , Natalia S Pellegata	2012-08-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21566140	Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore. J. Biol. Chem. Maoqing Dong , Polo C-H Lam , Delia I Pinon , Keiko Hosohata , Andrew Orry , Patrick M Sexton , Ruben Abagyan , Laurence J Miller	2011-07-08	Sct, Sctr
21388146	Importance of each residue within secretin for receptor binding and biological activity. Biochemistry Maoqing Dong , Angela Le , Jerez A Te , Delia I Pinon , Andrew J Bordner , Laurence J Miller	2011-04-12	Sct, Sctr
20927047	Central and peripheral administration of secretin inhibits food intake in mice through the activation of the melanocortin system. Neuropsychopharmacology Carrie Yuen Yee Cheng , Jessica Yan Shuen Chu , Billy Kwok Chong Chow	2011-01-01	Sct, Sctr
18467541	Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding. Mol Pharmacol Maoqing Dong , Polo C-H Lam , Delia I Pinon , Patrick M Sexton , Ruben Abagyan , Laurence J Miller	2008-08-01	-

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