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81758 Rbl2

81758

Rbl2

RB transcriptional corepressor like 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition RB transcriptional corepressor like 2

研究结论

Date Results Publications
2010-01-21 00:00:00 RB2/p130 plays a role in the early neural differentiation of mysenchymal stem cells through histone deacetylases dependent pathways. 15459751
2010-01-21 00:00:00 PPARalpha trans-repression involved the recruitment of the retinoblastoma (RB) family proteins p107 and p130 to the TERT promoter resulting in impaired E2F-1 binding, an effect that was dependent on p16. 18818403
2010-01-21 00:00:00 Rb2 was found to have a role in neural differentiation but not in neural determination. 15174090
2010-01-21 00:00:00 data indicate that p53 can cooperate selectively with p130(Rb2) to induce cellular senescence, a pathway that may be relevant when the pRb/p16INK4a pathway is defunct 16123778
2010-01-21 00:00:00 p130-E2F4 complex recruits the chromatin modifiers HDAC1 and Suv39H1 to promote gene silencing and neuron survival. 15769944

名称对应

Type IDs
Synonymous Rb2
Gene
UniProtKB-ID: RBL2_RAT
UniprotKB: O55081
UniParc: UPI00001331DC
EMBL: D55627
KO: rno:81758
Nucleutide sequences
EMBL-CDS: BAA24196.1
Protein sequencees
RefSeq: XP_006255261.1, XP_006255262.1, NP_112356.2, XP_006255263.1
Others
UniRef100: UniRef100_O55081
UniRef90: UniRef90_O55081
UniRef50: UniRef50_Q08999
UniGene: Rn.11020

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Second University of Naples

3
2

National Cancer Institute

2
3

Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, E-28029 Madrid, Spain. malumbres@cnio.es

1
4

University of Kentucky College of Medicine

1
5

Massachusetts General Hospital Cancer Center and Harvard Medical School Laboratory of Molecular Oncology, Charlestown, MA, USA.

1
热点人员
排名 研究人员 文献
1

Antonio Giordano

2
2

Umberto Galderisi

2
3

Marilena Cipollaro

2
4

S S Thorgeirsson

1
5

J T Woitach

1
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