| Type | Description |
|---|---|
| Definition | presenilin 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 11:22:00 | Downregulating the expression of miR-375, miR-30a, and miR-34a restored PSEN1, PSEN2, and NICD1 production and prevented glucotoxicity-induced impairment of the beta cells.Our findings demonstrated that miRNA-mediated suppression of NICD1 links the presenilin/Notch1 pathway to glucotoxicity in mature pancreatic beta cells | 27804997 |
| 2016-10-01 11:51:00 | Significant dysregulation of presenilin 2 gene was found in neuronal cells following brain ischemia due to cardiac arrest. | 26721367 |
| 2010-01-21 00:00:00 | The finding of presenilin-2 in the heart and the responsiveness to low glucose and hypoxia suggests that PS2 may be regulated by conditions of ischemia, a condition which both the heart and brain may experience. | 12468103 |
| 2010-01-21 00:00:00 | Ablation of presenilins results in deficiency of CD8 cells in the periphery and a dramatic change in the physiology of thymocytes. | 17626841 |
| 2010-01-21 00:00:00 | Calmyrin binds specifically endogenous preseninin-2 (PS2) and not PS1. | 16257512 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PSN2_RAT
UniprotKB:
O88777
UniParc:
UPI00001327DD
EMBL:
AB004454,
X99267,
D83700,
BC078805
Ensembl:
ENSRNOG00000002879
KO:
rno:81751
|
| Nucleutide sequences |
EMBL-CDS:
BAA20406.1,
AAH78805.1,
BAA22832.1,
CAA67663.1
Ensembl_TRS:
ENSRNOT00000040203,
ENSRNOT00000091715
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000049605,
ENSRNOP00000070964
RefSeq:
XP_006250472.1,
XP_006250469.1,
XP_017454428.1,
NP_112349.2,
XP_006250467.1,
XP_006250470.1,
XP_008768099.1
|
| Others |
UniRef100:
UniRef100_O88777
UniRef90:
UniRef90_P49810
UniRef50:
UniRef50_P49810
UniGene:
Rn.11045
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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