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8174 MADCAM1

8174

MADCAM1

mucosal vascular addressin cell adhesion molecule 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition mucosal vascular addressin cell adhesion molecule 1

研究结论

Date Results Publications
2021-01-16 15:58:00 Baseline levels of dynamic CD4(+) T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study. 32293299
2020-06-20 12:57:00 n the present study, mucosal addressin cell adhesion molecule-1 was selectively expressed on alpha-smooth muscle actin-positive reticular framework. The reticular framework may function in lymphocyte homing and segregation into the periarteriolar lymphoid sheath, lymph follicle and marginal zone. 31866620
2016-12-24 10:13:00 Both the ACT-1 assay and the MAdCAM-1 assay demonstrated acceptable reproducibility and repeatability. The assays were sufficiently stable to allow for clinical use. During clinical testing the assays demonstrated that vedolizumab was able to saturate peripheral cells at all doses tested. 25908521
2016-08-13 10:23:00 Doxo-induced apoptosis has a role in inhibiting hepatocellular carcinoma by targeting Madcam1 and AKT and blocking protein translation initiation 26124182
2013-11-30 10:47:00 MADCAM1 is up-regulated in liver cirrhosis with expression on peribiliary vascular plexus and lymphoid aggregates 23839340

名称对应

Type IDs
Synonymous MACAM1
Gene
UniProtKB-ID: MADCA_HUMAN
UniprotKB: Q13477
UniParc: UPI000013C68F, UPI0000452191, UPI000013EBB7, UPI000185D561
EMBL: CH471242, U80014, BC142629, BC137506, BC144065, AC005775, U43628, U80012, U80013, AY732484, BC137507, U80015, U82483, U80016
Ensembl: ENSG00000099866
KO: hsa:8174
Nucleutide sequences
EMBL-CDS: AAV33123.1, EAW61195.1, AAC51354.1, AAI44066.1, AAI37508.1, AAC62844.1, AAI42630.1, AAI37507.1, AAB02194.1, AAC13661.1
Ensembl_TRS: ENST00000215637, ENST00000382683, ENST00000346144
Protein sequencees
Ensembl_PRO: ENSP00000215637, ENSP00000372130, ENSP00000304247
RefSeq: NP_570118.1, NP_570116.2
Others
UniRef100: UniRef100_Q13477
UniRef90: UniRef90_Q13477
UniRef50: UniRef50_Q13477
UniGene: Hs.102598
CCDS: CCDS12028.1, CCDS12029.1

全选

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研究热度

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