| Type | Description |
|---|---|
| Definition | gamma-glutamyl carboxylase |
| Date | Results | Publications |
|---|---|---|
| 2018-01-13 13:11:00 | In a rat model of chronic kidney disease, there was a decrease in the thoracic aorta expression of Vkor and Ggcx enzymes, and a decrease in the kidney level of vitamin K1 to MK-4 bioconversion enzyme Ubiad1. | 27846632 |
| 2017-10-14 11:18:00 | gamma-Carboxylase inhibition prevents osteocalcin carboxylation and protects against diabetic cardiomyopathy, possibly through direct action on upregulated G protein-coupled receptor family C group 6 member A and indirectly via adiponectin. | 27488359 |
| 2013-08-03 11:28:00 | reduced gamma-Carboxylated MGP (cMGP), through an impaired expression of gamma-carboxylase, is involved in the early development of Medial artery calcification (MAC)in diabetes. | 23118128 |
| 2010-01-21 00:00:00 | Both carboxylase activity and formation of gamma-carboxyglutamate (Gla)-containing proteins were stimulated by dexamethasone (Dex) in fetal type II lung cells | 12754193 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
VKGC_RAT,
Q497C4_RAT
UniprotKB:
O88496,
Q497C4
UniParc:
UPI0000138887,
UPI0000574FF9
EMBL:
BC100621,
AC120568,
AF065387
Ensembl:
ENSRNOG00000012975
KO:
rno:81716
|
| Nucleutide sequences |
EMBL-CDS:
AAC82374.1,
AAI00622.1
Ensembl_TRS:
ENSRNOT00000084281
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000072920
RefSeq:
XP_017448398.1,
NP_113944.1,
XP_017448399.1
|
| Others |
UniRef100:
UniRef100_O88496,
UniRef100_Q497C4
UniRef90:
UniRef90_O88496,
UniRef90_Q497C4
UniRef50:
UniRef50_A0A1U8D508,
UniRef50_P38435
UniGene:
Rn.22410
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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