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8170 SLC14A2

8170

SLC14A2

solute carrier family 14 member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 14 member 2

研究结论

Date Results Publications
2018-07-28 11:15:00 The urea transporter subtypes, UT-A1 and UT-B1, were expressed in the skin basal cell layer and exocrine sweat glands. The abundance of UT-A1 and UT-B1 in uremic sweat glands was significantly increased in UP, while the expression of AQP5 was decreased. 29279852
2016-08-20 10:40:00 UT2 is a negative regulator shared across and mTORC2 signaling cascades, functioning as a tumor suppressor in hematologic malignancies driven by those pathways. 26927669
2015-05-02 12:28:00 Studies indicate that the cell signaling pathway for vasopressin-mediated urea transporters phosphorylation and activity involves two cAMP-dependent signaling pathways. 25298341
2015-05-02 12:28:00 Studies indicate that osmotic diuresis, where urea concentrations are low, can prompt an increase in urea transporter abundance. 25298340
2015-05-02 12:28:00 Studies indicate that the urea transporter SLC14a2, the UT-A group, was originally isolated from kidney inner medulla. 25298338

名称对应

Type IDs
Synonymous HUT2, UT-A2, UT2, UTA, UTR, hUT-A6
Gene
UniProtKB-ID: UT2_HUMAN
UniprotKB: Q15849
UniParc: UPI0000137E5E, UPI000013CE99
EMBL: AF349446, BC110446, AC023421, AK292422, X96969
Ensembl: ENSG00000132874
KO: hsa:8170
Nucleutide sequences
EMBL-CDS: BAF85111.1, CAA65657.1, AAI10447.1, AAL08485.1
Ensembl_TRS: ENST00000255226, ENST00000586448
Protein sequencees
Ensembl_PRO: ENSP00000465953, ENSP00000255226
RefSeq: NP_001358248.1, NP_001229621.1, NP_009094.3, XP_024307038.1, XP_024307039.1, XP_016881505.1
Others
UniRef100: UniRef100_Q15849
UniRef90: UniRef90_Q15849
UniRef50: UniRef50_Q15849
UniGene: Hs.710927
CCDS: CCDS11924.1

全选

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