| Type | Description |
|---|---|
| Definition | A-kinase anchoring protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | Induction of UCP1 and thermogenesis by a small molecule via modulation. | 32855239 |
| 2021-01-16 15:54:00 | A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. | 32482893 |
| 2019-05-11 11:51:00 | depletion of "signaling islands" from the outer mitochondrial membrane augments progression toward metastatic breast cancer | 30598507 |
| 2018-03-10 11:27:00 | AKAP1 is a transcriptional target of Myc, and it supports mTOR pathway and the growth of cancer cells. | 28569781 |
| 2017-05-27 11:04:00 | Furthermore, we discuss the role of hypoxia in prompting cellular stress and damage, which has been demonstrated to mediate the proteosomal degradation of AKAP121, leading to an increase in reactive oxgyen species production, mitochondrial dysfunction, and ultimately cell death. [review] | 26825124 |
| Type | IDs |
|---|---|
| Synonymous | AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, TDRD17 |
| Gene |
UniProtKB-ID:
AKAP1_HUMAN,
B4DN86_HUMAN,
A0A140VK05_HUMAN
UniprotKB:
Q92667,
B4DN86,
A0A140VK05
UniParc:
UPI0000125778,
UPI00017A7738,
UPI000002A392
EMBL:
BC000729,
U34074,
AK297810,
CH471109,
X97335,
HM005545,
AK292416
Ensembl:
ENSG00000121057
KO:
hsa:8165
|
| Nucleutide sequences |
EMBL-CDS:
AAH00729.1,
EAW94518.1,
EAW94516.1,
EAW94515.1,
CAA66000.1,
AAC50279.1,
BAF85105.1,
BAG60148.1,
AEE61142.1
Ensembl_TRS:
ENST00000314126,
ENST00000621116,
ENST00000539273,
ENST00000481416,
ENST00000572557,
ENST00000571629,
ENST00000337714
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000314075,
ENSP00000433212,
ENSP00000459968,
ENSP00000337736,
ENSP00000443139,
ENSP00000459895,
ENSP00000478212
RefSeq:
NP_003479.1,
NP_001357352.1,
NP_001229832.1,
NP_001357355.1,
XP_024306728.1,
XP_016880679.1,
NP_001357353.1,
NP_001357354.1,
NP_001357356.1,
NP_001229831.1
|
| Others |
UniRef100:
UniRef100_Q92667,
UniRef100_B4DN86
UniRef90:
UniRef90_Q92667
UniRef50:
UniRef50_Q92667
UniGene:
Hs.463506
CCDS:
CCDS11594.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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