| Type | Description |
|---|---|
| Definition | heavy metal atpase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 12:06:00 | Homology modeling of the HMA4 transmembrane region based on the crystal structure of a ZntA bacterial homolog highlighted amino acids forming a metal permeation pathway. Although the zinc pathway displayed overall conservation among the two proteins, significant differences were observed, especially in the entrance area with altered electronegativity and the presence of a ionic interaction/hydrogen bond network. | 30418580 |
| 2019-10-19 12:53:00 | di-Cys motifs, but not the His-stretch, contribute to high affinity zinc binding and function in planta. We suggest that the HMA4 C-terminal extension is at least partly responsible for protein targeting to the plasma membrane. | 30137564 |
| 2018-01-27 11:02:00 | To test whether developing Arabidopsis seeds depend on AtHMA2 and AtHMA4 for proper zinc unloading from the seed coat, the authors analysed the amount of zinc present in the maternal and filial parts of the seed, respectively, in wild-type and mutant seeds lacking functional AtHMA2, AtHMA4, or both. | 27243644 |
| 2017-11-18 13:02:00 | overexpression modulates the ratio of Zn to Cd supply as a determinant of metal-homeostasis gene expression in tobacco | 27811086 |
| 2016-07-16 11:40:00 | These studies evaluated the the function and structure of the N-terminal cytoplasmic metal-binding domain of HMA4. | 26797794 |
| Type | IDs |
|---|---|
| Synonymous | ARABIDOPSIS HEAVY METAL ATPASE 4, ATHMA4, T20K24.12, T20K24_12, heavy metal atpase 4 |
| Gene |
UniProtKB-ID:
HMA4_ARATH,
Q0WUP4_ARATH,
A0A384L331_ARATH
UniprotKB:
O64474,
Q0WUP4,
A0A384L331
UniParc:
UPI000000119F
EMBL:
AC002392,
CP002685,
AJ297264,
LUHQ01000002,
AK227102,
AY096796
EnsemblGenome:
AT2G19110
KO:
ath:AT2G19110
|
| Nucleutide sequences |
EMBL-CDS:
ANM62252.1,
ANM62253.1,
CAC19544.1,
AAD12041.1,
AAM19954.1,
AEC06848.1,
BAE99154.1,
OAP10298.1
Gene_ORFName:
T20K24.12
EnsemblGenome_TRS:
AT2G19110.2,
AT2G19110.3,
AT2G19110.1
|
| Protein sequencees |
EnsemblGenome_PRO:
AT2G19110.1,
AT2G19110.2,
AT2G19110.3
RefSeq:
NP_001324425.1,
NP_001318247.1,
NP_179501.1
|
| Others |
UniRef100:
UniRef100_O64474
UniRef90:
UniRef90_O64474
UniRef50:
UniRef50_O64474
UniGene:
At.25023
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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