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81624 DIAPH3

81624

DIAPH3

diaphanous related formin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition diaphanous related formin 3

研究结论

Date Results Publications
2020-10-24 13:56:00 Tropomyosin concentration but not formin nucleators mDia1 and mDia3 determines the level of tropomyosin incorporation into actin filaments. 31019238
2020-06-20 11:24:00 The oncogenic roles of DIAPH3 in the tumorigenesis of lung cance. 31586548
2019-04-13 10:05:00 through profilin-1 binding, CLIC4 functions in a RhoA-mDia2-regulated signaling network to integrate cortical actin assembly and membrane protrusion 30381396
2018-09-01 10:37:00 These data identify Diaph3 as a major guard of cortical progenitors, unravel novel functions of Diaphanous formins and add insights into the pathobiology of microcephaly. 27848932
2018-07-14 10:54:00 study demonstrated the oncogenic activity of DIAPH3 in the progression of hepatocellular carcinoma and suggested that PDIAPH3 might be a therapeutic target. 28795316

名称对应

Type IDs
Synonymous AN, AUNA1, DIA2, DRF3, NSDAN, diap3, mDia2
Gene
UniProtKB-ID: DIAP3_HUMAN, B4DPV3_HUMAN
UniprotKB: Q9NSV4, B4DPV3
UniParc: UPI0000D8A24B, UPI000015FC7C, UPI00017A77B1, UPI0000E59B04, UPI0000E59B03, UPI0000DAC774, UPI0000062317, UPI0000695D70
EMBL: AL354829, AY750055, AY818645, AL356502, AK298509, BC034952, BC048963, BC068504, AB244756, AL390878, BX649186, AK092024, AB244758, AL137718, AB244757, AL359266
Ensembl: ENSG00000139734
KO: hsa:81624
Nucleutide sequences
EMBL-CDS: BAE96350.1, AAW73254.1, BAC03793.1, BAE96352.1, AAH68504.1, AAH48963.1, AAW78862.1, BAE96351.1, CAE46204.1, CAB70890.1, AAH34952.1, BAG60715.1
Ensembl_TRS: ENST00000267215, ENST00000377908, ENST00000498416, ENST00000465066, ENST00000400324, ENST00000400320, ENST00000400319
Protein sequencees
Ensembl_PRO: ENSP00000383174, ENSP00000367141, ENSP00000383178, ENSP00000267215, ENSP00000383173, ENSP00000478137, ENSP00000479091
RefSeq: XP_011533560.1, XP_016876278.1, XP_011533567.1, NP_001245297.1, NP_001245296.1, NP_001245299.1, XP_024305190.1, NP_001245298.1, NP_112194.2, NP_001245295.1, XP_006719939.1, NP_001035982.1, XP_011533565.1
Others
UniRef100: UniRef100_Q9NSV4, UniRef100_B4DPV3
UniRef90: UniRef90_Q9NSV4
UniRef50: UniRef50_Q9Z207
UniGene: Hs.283127
CCDS: CCDS58297.1, CCDS58294.1, CCDS58296.1, CCDS41898.1, CCDS58295.1, CCDS73580.1, CCDS73579.1

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